Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

Table 1 Twelve polymorphisms genotyped in this study.

Gene	Name	dbSNP rs#	Region	Allele	Methods
SYN2	SYN2-1	rs2623873	Promoter	G/T	Direct Sequencing
SYN2	SYN2-2	rs2308169	Intron	ATGCT/-	Direct Sequencing
SYN2	SYN2-3	rs308961	Intron	T/G	Direct Sequencing
SYN2	SYN2-4	rs308963	Intron	C/G	Direct Sequencing
SYN2	SYN2-5	rs308952	Intron^a	A/G	Dde I RFLP
SYN2	SYN2-6	rs2279750	Intron^a	A/C	Direct Sequencing
SYN2	SYN2-7	rs310762	Intron	C/T	Direct Sequencing
CPLX2	CPLX2-1	rs2247916	Promoter	G/T	Mae III RFLP
CPLX2	CPLX2-2	rs2243404	5'UTR	C/T	Cac 8I RFLP
CPLX2	CPLX2-3	rs890736	Intron	C/T	Ava II RFLP
CPLX2	CPLX2-4	rs890737	Intron	C/T	Direct Sequencing
CPLX2	CPLX2-5	rs4390706	Intron	G/A	Direct Sequencing

^a Tissue inhibitor of metalloproteinase 4 (Timp4) gene is nested within the intron of SYN2 in reverse orientation.

ISSN: 1744-9081