Figure 1From: Cystathionine β-synthase T833C/844INS68 polymorphism: a family-based study on mentally retarded childrenRepresentation of double mutation in exon 8 of CBS gene: lane 1 = homozygous genotype without insertion, lane 2 = heterozygous genotype with 68 bp insertion, lane 3 = φX174 HaeIII digest showing bands at 310, 281, 234,194 and 118 respectively, lane 4 = BsrI digestion of heterozygous PCR product (of lane 2), showing complete digestion of the higher allele of 239 bp into 130 bp and 109 bp.Back to article page