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Table 2 ROC-curve of mercury (μg/L), lead (μg/dl), GST (μmol/l) and vitamin E (nmol/L) levels in the autistic groups

From: A key role for an impaired detoxification mechanism in the etiology and severity of autism spectrum disorders

Parameters

Autistic patients

CARS

SRS

Mild to moderate

Severe

Mild to moderate

Severe

Mercury

Area under the curve

0.926

0.961

1.000

0.935

0.997

 

Best cutoff value

6.018

6.018

6.316

6.105

6.346

 

Sensitivity %

84.5%

93.1%

100.0%

86.4%

95.5%

 

Specificity %

93.8%

93.8%

100.0%

96.9%

100.0%

Lead

Area under the curve

0.953

0.917

0.980

0.923

0.980

 

Best cutoff value

5.586

5.590

6.132

6.132

6.321

 

Sensitivity %

89.7%

79.3%

89.3%

72.7%

86.4%

 

Specificity %

87.5%

87.5%

96.9%

96.9%

100.0%

GST

Area under the curve

0.980

0.974

1.000

0.983

1.000

 

Best cutoff value

0.443

0.443

0.320

0.443

0.320

 

Sensitivity %

100.0%

100.0%

100.0%

100.0%

100.0%

 

Specificity %

93.3%

93.3%

100.0%

93.3%

100.0%

Vitamin E

Area under the curve

0.999

1.000

1.000

1.000

1.000

 

Best cutoff value

19.254

18.718

18.089

18.718

17.953

 

Sensitivity %

96.4%

100.0%

100.0%

100.0%

100.0%

 

Specificity %

100.0%

100.0%

100.0%

100.0%

100.0%