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Table 3 Associations of genotypes with smoking initiation age (in years), daily cigarette consumption (in cigarettes per day) and FTND score as continuous traits

From: Association between Common Genetic Variants in the Opioid Pathway and Smoking Behaviors in Chinese Men

Genotype Smoking initiation agea Daily cigarette consumptiona FTND scoreac
rs1799971    
AA 25.8 ± 9.3 20.6 ± 10.3 4.1 ± 2.6
AG 25.9 ± 10.1 22.1 ± 12.0 3.5 ± 2.6
GG 27.6 ± 11.0 18.9 ± 8.9 2.7 ± 2.2
β Coefficient (se) 0.05 (1.00) 0.48 (0.84) –0.63 (0.35)
P valueb 0.96 0.56 0.07
rs3786047    
AA 26.0 ± 11.8 21.7 ± 17.6 8.0 ± 0.0
AG 24.9 ± 10.2 21.1 ± 9.8 3.9 ± 2.7
GG 26.5 ± 9.7 21.0 ± 11.4 3.6 ± 2.5
β Coefficient (se) 0.05 (1.36) –1.11 (1.13) 0.58 (0.47)
P valueb 0.97 0.33 0.22
rs1045280    
CC 23.5 ± 10.8 21.3 ± 14.4 5.0 ± 4.2
CT 24.8 ± 10.2 21.1 ± 9.8 3.9 ± 2.6
TT 26.6 ± 9.7 21.1 ± 11.4 3.6 ± 2.5
β Coefficient (se) –0.14 (1.33) –1.16 (1.11) 0.45 (0.45)
P valueb 0.92 0.29 0.32
rs2036657    
AA 26.6 ± 9.6 21.2 ± 11.4 3.7 ± 2.6
AG 24.9 ± 10.2 20.8 ± 9.7 3.8 ± 2.6
GG 21.6 ± 10.3 21.0 ± 12.4 5.0 ± 4.2
β Coefficient (se) –0.39 (1.31) –1.35 (1.09) 0.32 (0.45)
P valueb 0.76 0.22 0.49
rs3852209    
CC 26.4 ± 10.5 21.2 ± 11.5 3.5 ± 2.5
CT 25.5 ± 8.7 21.2 ± 10.1 4.2 ± 2.6
TT 24.9 ± 7.9 18.8 ± 9.0 2.5 ± 2.6
β Coefficient (se) –0.60 (1.11) –0.69 (0.93) 0.19 (0.38)
P valueb 0.59 0.46 0.62
rs2278060    
AA 26.3 ± 10.6 21.4 ± 11.7 3.5 ± 2.5
AC 25.9 ± 8.6 20.9 ± 9.9 4.2 ± 2.6
CC 23.9 ± 8.4 18.9 ± 8.7 2.4 ± 2.4
β Coefficient (se) –0.86 (1.09) –0.70 (0.92) 0.12 (0.37)
P valueb 0.43 0.44 0.75
  1. aValues are means ± SD.
  2. bLinear regression models were adjusted for age.
  3. cCurrent smokers.