Skip to main content

Advertisement

Table 1 Effects of rosiglitozane on IL-1b,IL-6,IL-10 and TNF-a content (n = 5)

From: PPAR-alpha and PPAR-beta expression changes in the hippocampus of rats undergoing global cerebral ischemia/reperfusion due to PPAR-gamma status

Group IL-1β IL-6 IL-10 TNF-α
  (mg/ml) (ng/ml) (ng/ml) (ng/ml)
sham control 218.35 ± 42.2 6.37 ± 0.43 3.01 ± 0.25 2.19 ± 0.35
IR 561.31 ± 49.98** 15.83 ± 1.37* 1.86 ± 0.15** 6.36 ± 1.11**
0.8 mg/kg Ros 505.11 ± 39.28** 13.27 ± 0.89** 2.81 ± 0.37** 5.57 ± 0.43**
2.4 mg/kg Ros 437.71 ± 51.74**## 10.27 ± 0.516**## 2.37 ± 0.25**## 4.23 ± 0.61**##
7.2 mg/kg Ros 390.22 ± 42.08## 8.05 ± 0.95## 2.01 ± 0.31## 3.39 ± 0.37##
7.2 mg/kg Ros plus GW9662 572.40 ± 33.27** 16.17 ± 1.12** 1.95 ± 0.17** 6.19 ± 1.01**
GW9662 in sham control 233.57 ± 28.33 6.07 ± 0.33 3.21 ± 0.35 2.45 ± 0.22
  1. Datas are expressed as mean ± SD (n = 5). * and **:P < 0.05 and 0.01, vs. sham control; # and ##:P < 0.05 and 0.01 vs. IR.