|
Group
|
IL-1β
|
IL-6
|
IL-10
|
TNF-α
|
|---|
| |
(mg/ml)
|
(ng/ml)
|
(ng/ml)
|
(ng/ml)
|
|---|
|
sham control
|
218.35 ± 42.2
|
6.37 ± 0.43
|
3.01 ± 0.25
|
2.19 ± 0.35
|
|
IR
|
561.31 ± 49.98**
|
15.83 ± 1.37*
|
1.86 ± 0.15**
|
6.36 ± 1.11**
|
|
0.8 mg/kg Ros
|
505.11 ± 39.28**
|
13.27 ± 0.89**
|
2.81 ± 0.37**
|
5.57 ± 0.43**
|
|
2.4 mg/kg Ros
|
437.71 ± 51.74**##
|
10.27 ± 0.516**##
|
2.37 ± 0.25**##
|
4.23 ± 0.61**##
|
|
7.2 mg/kg Ros
|
390.22 ± 42.08##
|
8.05 ± 0.95##
|
2.01 ± 0.31##
|
3.39 ± 0.37##
|
|
7.2 mg/kg Ros plus GW9662
|
572.40 ± 33.27**
|
16.17 ± 1.12**
|
1.95 ± 0.17**
|
6.19 ± 1.01**
|
|
GW9662 in sham control
|
233.57 ± 28.33
|
6.07 ± 0.33
|
3.21 ± 0.35
|
2.45 ± 0.22
|
- Datas are expressed as mean ± SD (n = 5). * and **:P < 0.05 and 0.01, vs. sham control; # and ##:P < 0.05 and 0.01 vs. IR.
