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Table 2 Haplotype analyses of KIAA0319 region using 2- or 3-markers sliding windows in association with categorical DD

From: A common haplotype of KIAA0319 contributes to the phonological awareness skill in Chinese children

Haplotypes

Frequency

Global p-values

Individual haplotype test

Adjusted P value

 

OR (95% CI)

p-values

Permutation (1000)

rs3756821- rs9366577

C-T

0.791

0.0625

1

0.0495

 

T-T

0.168

0.5323 (0.1866 – 1.519)

0.2568

T-C

0.040

0.3874 (0.1499 – 1.001)

0.0442

rs4504469 rs2038137 rs2143340

T-T-G

0.668

0.3579

0.3703 (0.0906 – 1.513)

0.4093

 

T-T-C

0.137

0.2569 (0.05752 – 1.148)

0.1736

 

A-G-G

0.077

0.2598 (0.05393 – 1.251)

0.3173

 

C-G-G

0.065

0.6415 (0.1436 – 2.866)

0.2752

 

A-C-G

0.033

1

  

A-G-C

0.014

0.1851 (0.02041 – 1.68)

0.4142

 

Sliding window

      

2-markers

      

rs9366577- rs2038139

C-A

0.041

0.0305

1

0.0116

0.3656

T-A

0.832

0.2667 (0.0885 – 0.8035)

0.3173

T-C

0.127

0.2333 (0.0669 – 0.8134)

0.6547

rs6915373-rs9467239

C-C

0.337

0.0375

1

0.3832

C-G

0.202

1.7480 (1.013 – 3.016)

0.0528

T-C

0.061

2.4560 (0.9815 – 6.145)

0.0878

T-G

0.401

0.9833 (0.6372 – 1.517)

0.1215

3-markers

      

rs9366577-rs2038139-rs2038137

C-A-G

0.040

0.02347

5 (1.447 – 17.27)

0.0047

0.3397

T-A-G

0.788

1

0.2041

T-A-T

0.053

1.265 (0.4706 – 3.402)

0.6171

T-C-T

0.110

0.7706 (0.374 – 1.588)

0.3692

4-markers

      

rs9366577-rs2038139-rs208137- rs3756821

C-A-G-T

0.041

0.0301

5.33 (1.535 – 18.53)

0.0047

0.4306

T-A-G-C

0.635

1

0.0330

T-A-G-T

0.156

1.654 (0.9109 – 3.005)

0.1489

T-A-T-C

0.042

1.809 (0.4949 – 6.614)

0.5271

 

T-C-T-C

0.109

 

0.859 (0.4114 – 1.793)

0.3692