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Table 1 Association between SNPs in DRD2 and dyslexia using the additive, dominant, genotype, and the recessive models

From: Stuttering candidate genes DRD2 but not SLC6A3 is associated with developmental dyslexia in Chinese population

  SNP Patient Control Crude OR (95%CI) Unadjusted Adjusted OR (95%CI) Adjusted p-value Bonferroni corrected p-value
rs2440390 C Allele 930 975 1   1   
T Allele 36 45 0.8436(0.5432-1.31) 0.4488 0.7823(0.4875-1.256) 0.3091 1
CC 449 466 1   1   
CT 32 43 0.7724(0.4800-1.2427) 0.2870905 0.7092(0.4247-1.1843) 0.18903 1
TT 2 1 2.0757(0.1877-22.9491) 0.5513879 1.8799(0.1540-22.9427) 0.62095 1
Dom    0.802(0.5033-1.278) 0.3533 0.7372(0.446-1.218) 0.2342 1
Rec    2.116(0.1913-23.42) 0.541 1.928(0.1574-23.6) 0.6076 1
rs1079727 T Allele 521 606 1   1   
C Allele 445 414 1.254(1.048-1.501) 0.01345 1.337(1.1-1.626) 0.003592 0.0828
TT 143 174 1   1   
CT 235 258 1.10831(0.8350-1.4711) 0.4765734 1.0949(0.8061-1.4871) 0.561809 1
CC 105 78 1.6380(1.1347-2.3645) 0.0084253 1.8827(1.2633-2.8059) 0.001883 0.0437*
Dom    1.231(0.9421-1.609) 0.1277 1.269(0.9509-1.694) 0.1056 1
Rec    1.538(1.113-2.127) 0.009134 1.816(1.272-2.592) 0.001017 0.023*
rs2002453 T Allele 476 539 1   1   
C Allele 490 475 1.169(0.9793-1.396) 0.0838 1.238(1.022-1.5) 0.02946 0.6785
TT 123 136 1   1   
CT 230 267 0.9525(0.7049-1.2869) 0.7511201 0.9340(0.6743-1.2938) 0.681255 1
CC 130 104 1.3821(0.9692-1.9710) 0.073918 1.5311(1.0454-2.2424) 0.028655 0.6601
Dom    1.073(0.8079-1.425) 0.6269 1.1(0.81-1.494) 0.5414 1
Rec    1.427(1.063-1.916) 0.01806 1.633(1.183-2.253) 0.002867 0.0667
rs2471851 A Allele 565 641 1   1   
C Allele 399 377 1.205(1.004-1.446) 0.04551 1.269(1.041-1.549) 0.01864 0.4278
AA 165 198 1   1   
AC 235 245 1.1510(0.8757-1.5128) 0.3131888 1.1008(0.8188-1.4799) 0.524907 1
CC 82 66 1.4909(1.0151-2.1897) 0.0416912 1.7458(1.1457-2.6601) 0.009509 0.2185
Dom    1.223(0.9439-1.585) 0.1276 1.225(0.9262-1.62) 0.1548 1
Rec    1.376(0.9685-1.955) 0.07486 1.67(1.134-2.459) 0.009401 0.2162
rs12800853 C Allele 921 959 1   1   
T Allele 43 61 0.7304(0.4877-1.094) 0.1276 0.723(0.4698-1.113) 0.1403 1
CC 439 451 1   1   
CT 43 57 0.7750(0.5107-1.1762) 0.2310594 0.7807(0.4999-1.2194) 0.276544 1
TT 0 2 NA   NA   
Dom    0.7487(0.4947-1.133) 0.1711 0.7476(0.4802-1.164) 0.1978 1
Rec        
rs17115583 G Allele 560 549 1   1   
A Allele 406 459 0.8636(0.7207-1.035) 0.1119 0.8382(0.6894-1.019) 0.07648 1
GG 167 138 1   1   
AG 226 273 0.6841(0.5138-0.9108) 0.009318 0.6686(0.4892-0.9138) 0.01156 0.2668
AA 90 93 0.7997(0.5539-1.1545) 0.2328118 0.7555(0.5102-1.1189) 0.161701 1
Dom    0.7135(0.544-0.9356) 0.01465 0.6914(0.5152-0.9279) 0.01393 0.3197
  Rec    1.012(0.7341-1.395) 0.9416 0.9593(0.6786-1.356) 0.8141 1
rs11214607 T Allele 589 674 1   1   
G Allele 377 346 1.247(1.038-1.499) 0.01845 1.324(1.084-1.616) 0.005965 0.138
TT 177 225 1   1   
GT 235 224 1.3336(1.0192-1.7450) 0.0358259 1.3111(0.9822-1.7501) 0.066015 1
GG 71 61 1.4796(0.9969-2.1958) 0.0517832 1.8187(1.1654-2.8382) 0.00844 0.1932
Dom    1.365(1.058-1.761) 0.01663 1.398(1.062-1.84) 0.01696 0.391
Rec    1.268(0.8785-1.832) 0.2045 1.53(1.022-2.292) 0.03885 0.8947
rs12574471 C Allele 831 873 1   1   
T Allele 135 143 0.9917(0.7683-1.28) 0.9488 0.9854(0.7477-1.299) 0.9166 1
CC 358 373 1   1   
CT 115 127 0.9435(0.7052-1.2621) 0.6950158 0.9483(0.6924-1.2988) 0.740855 1
TT 10 8 1.3024(0.5083-3.3372) 0.5821073 1.2050(0.4383-3.3130) 0.717837 1
Dom    0.9647(0.7268-1.281) 0.8037 0.9643(0.7098-1.31) 0.8162 1
Rec    1.321(0.5171-3.376) 0.5605 1.218(0.4417-3.359) 0.703 1
rs4274224 A Allele 811 833 1   1   
G Allele 155 187 0.8478(0.6689-1.075) 0.1723 0.8359(0.6466-1.081) 0.1713 1
AA 338 339 1   1   
AG 135 155 0.8735(0.6631-1.1507) 0.3362564 0.8612(0.6392-1.1602) 0.325729 1
GG 10 16 0.6268(0.2805-1.4010) 0.2550209 0.6131(0.2577-1.4590) 0.268747 1
Dom    0.8505(0.6507-1.111) 0.2356 0.8399(0.6288-1.122) 0.2374 1
Rec    0.6527(0.2933-1.453) 0.296 0.6246(0.2631-1.483) 0.2862 1
rs7131056 C Allele 562 583 1   1   
A Allele 402 437 0.9565(0.8039-1.138) 0.6159 0.9669(0.8009-1.167) 0.7259 1
CC 166 177 1   1   
AC 230 229 1.0709(0.8095-1.4168) 0.6313223 1.0434(0.7684-1.4168) 0.78544 1
AA 86 104 0.8817(0.6179-1.2582) 0.4877891 0.9131(0.6228-1.3387) 0.64142 1
Dom    1.012(0.7788-1.315) 0.9298 1.005(0.7573-1.333) 0.9743 1
Rec    0.8478(0.6172-1.165) 0.308 0.8876(0.6292-1.252) 0.4969 1
rs72999677 G Allele 679 730 1   1   
C Allele 287 290 1.059(0.8792-1.275) 0.5477 1.099(0.8983-1.343) 0.3599 1
GG 245 273 1   1   
CG 189 184 1.14457(0.8769-1.4939) 0.320458 1.1395(0.8519-1.5242) 0.378904 1
CC 49 53 1.0302(0.6735-1.5758) 0.8909049 1.1518(0.7287-1.8206) 0.545185 1
Dom    1.119(0.8722-1.436) 0.3766 1.143(0.8731-1.496) 0.3307 1
  Rec    0.9735(0.6461-1.467) 0.8979 1.1(0.7044-1.716) 0.6762 1
  1. *P < 0.05, Bold data: adjusted p value < 0.05.