Skip to main content

Table 1 Effects of high cholesterol diets on serum biochemical parameters in young and adult rats

From: Age-dependent effect of high cholesterol diets on anxiety-like behavior in elevated plus maze test in rats

Biochemical parameters

Young

Adult

Control (n = 10)

HCD (n = 10)

Control (n = 10)

HCD (n = 10)

Initial weight (g)

76.57 ± 2.78

77.70 ± 2.80

553.33 ± 16.10

557.60 ± 17.48

Final weight (g)

395.81 ± 10.74

413.96 ± 7.59

610.84 ± 21.29

643.68 ± 24.40

TC (mmol/L)

1.85 ± 0.11

3.18 ± 0.18*

1.74 ± 0.08

2.38 ± 0.22*

HDL-C (mmol/L)

1.14 ± 0.06

0.95 ± 0.02*

0.97 ± 0.09

0.72 ± 0.06*

LDL-C (mmol/L)

0.42 ± 0.04

2.01 ± 0.16*

0.44 ± 0.04

1.38 ± 0.17*

Glucose (mmol/L)

8.77 ± 0.46

7.96 ± 0.58

7.78 ± 0.36

7.65 ± 0.22

ALT (U/L)

65.00 ± 4.10

94.2 ± 13.43*

62.3 ± 5.11

92.6 ± 9.55*

AST (U/L)

180.3 ± 21.04

221.5 ± 45.20

148.6 ± 15.16

160.4 ± 18.84

  1. Control: regular diet; HC: high cholesterol diet.
  2. The data are shown as the mean ± S.E.M. *P < 0.05 compared to the respective control group that fed the regular diet.