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Table 4 Comparison of body weight and BMI between different genotypes

From: Fat-mass and obesity-associated gene polymorphisms and weight gain after risperidone treatment in first episode schizophrenia

Characteristics

rs9939609

rs8050136

rs1421085

rs9930506

AA + AT

TT

T or x2

P

AA + AC

CC

t or x2

p

CC + CT

TT

t or x2

p

GG + AG

AA

t or x2

p

Male/female (n)

27/23

101/86

0.000

0.999

25/21

103/88

0.003

0.959

25/23

103/86

0.090

0.764

35/34

93/75

0.423

0.516

Age (years)

29.0 ± 7.5

26.9 ± 6.8

−1.819

0.07

29.1 ± 7.7

26.9 ± 6.8

−1.912

0.057

27.8 ± 7.5

27.3 ± 6.9

−0.427

0.67

27.7 ± 7.3

27.2 ± 6.9

−0.487

0.627

Age of illness onset (years)

26.2 ± 5.5

24.7 ± 4.7

1.949

0.053

26.3 ± 5.6

24.7 ± 4.7

1.772

0.81

24.8 ± 5.2

25.1 ± 4.9

−0.393

0.695

24.9 ± 4.8

25.0 ± 5.0

−0.174

0.86

Disease duration (months)

6.6 ± 4.9

7.5 ± 4.2

−1.334

0.183

6.5 ± 4.2

7.6 ± 4.3

−1.517

0.131

7.1 ± 3.9

7.4 ± 4.4

−0.427

0.670

7.5 ± 4.4

7.5 ± 4.3

0.411

0.682

Education (years)

13.3 ± 2.5

13.2 ± 3.0

−0.246

0.806

13.3 ± 2.6

13.2 ± 3.0

−0.296

0.767

13.2 ± 3.0

13.2 ± 2.9

−0.104

0.917

13.6 ± 3.1

13.0 ± 2.9

−1.223

0.223

Baseline

                

Weight (kg)

63.0 ± 10.8

59.5 ± 10.1

2.14

0.033*

62.6 ± 10.9

59.7 ± 10.2

1.707

0.089

61.7 ± 10.1

59.9 ± 10.4

1.065

0.288

58.2 ± 10.1

61.1 ± 10.4

−2.012

0.045*

BMI(kg/m2)

22.4 ± 3.2

21.2 ± 2.8

2.383

0.020*

22.3 ± 3.3

21.3 ± 2.8

1.955

0.055

22.1 ± 3.0

21.3 ± 2.9

1.637

0.103

21.0 ± 3.0

21.7 ± 2.9

−1.7272

0.085

Six months

                

Weight (kg)

71.7 ± 10.3

67.0 ± 9.8

2.949

0.004*

71.1 ± 10.4

67.2 ± 9.9

2.354

0.019*

68.9 ± 9.8

67.7 ± 10.1

0.714

0.476

65.8 ± 10.0

68.9 ± 9.984

−2.132

0.034*

BMI (kg/m2)

25.5 ± 3.0

23.9 ± 2.7

3.628

0.000*

25.4 ± 3.0

24.0 ± 2.7

3.009

0.003*

24.7 ± 2.8

24.2 ± 2.8

1.215

0.226

23.8 ± 3.0

24.5 ± 2.7

−1.786

0.075

  1. BMI, body mass index.
  2. *P<0.05.