Table 1 List of ENU-induced mutations in G1 mouse of Disc1<Rgsc1390>

Pkhd1

1

20,530,613

T → A

AT to TA transversions

Intronic

Trak2

1

58,975,614

A → G

AT to GC transitions

Essential splice site

Als2

1

59,235,933

A → T

AT to TA transversions

Stop gained

Y- > X

Ngef

1

89,379,202

A → T

AT to TA transversions

Nonsysnonymous

I- > N

2310035C23Rik

1

107,592,127

A → G

AT to GC transitions

Intronic

Ikbke

1

133,172,385

C → A

GC to TA transversions

Nonsysnonymous

A- > S

Cdc73

1

145,542,523

A → T

AT to TA transversions

Nonsysnonymous

S- > T

Nmnat2

1

154,936,083

A → T

AT to TA transversions

Intronic

Atf6

1

172,724,783

G → A

GC to AT transitions

Intronic

Gm5706

1

184,322,753

A → G

AT to GC transitions

Genic

Iars2

1

187,127,260

A → T

AT to TA transversions

Nonsysnonymous

I- > N

Dhtkd1

2

5,831,429

A → G

AT to GC transitions

Synonymous

Cacna1b

2

24,506,396

A → G

AT to GC transitions

Intronic

Dolk

2

30,140,520

A → G

AT to GC transitions

Synonymous

Lrp1b

2

40,854,333

A → C

AT to CG transversions

Intronic

Neb

2

52,114,402

C → A

GC to TA transversions

Nonsysnonymous

R- > L

Gm13559

2

58,593,845

A → G

AT to GC transitions

Genic

Ttn

2

76,553,805

C → T

GC to AT transitions

Nonsysnonymous

M- > I

Olfr1270

2

89,989,253

T → C

AT to GC transitions

Synonymous

Ext2

2

93,558,064

C → T

GC to AT transitions

Intronic

Ryr3

2

112,701,983

C → A

GC to TA transversions

Nonsysnonymous

G- > W

Fmn1

2

113,528,228

T → A

AT to TA transversions

Intronic

Sel1l2

2

140,071,126

C → T

GC to AT transitions

Nonsysnonymous

A- > T

Setd7

3

51,334,212

T → C

AT to GC transitions

Intronic

Ift80

3

68,794,587

A → T

AT to TA transversions

Intronic

Asb17

3

153,516,522

G → A

GC to AT transitions

3' UTR

4

8,394,708

T → C

AT to GC transitions

Intergenic

Esrp1

4

11,277,315

G → T

GC to TA transversions

Intronic

Gm136

4

34,699,557

C → T

GC to AT transitions

Nonsysnonymous

A- > T

Nfx1

4

40,952,108

T → A

AT to TA transversions

Intronic

Gm12608

4

89,109,036

T → A

AT to TA transversions

Genic

Tek

4

94,516,374

T → A

AT to TA transversions

Nonsysnonymous

S- > T

Dnajc6

4

101,279,103

C → T

GC to AT transitions

Intronic

Txndc12

4

108,533,802

T → A

AT to TA transversions

Intronic

Gm12901

4

122,935,965

T → C

AT to GC transitions

Genic

Tmprss11e

5

87,156,236

C → T

GC to AT transitions

Intronic

Ccng2

5

93,697,763

T → C

AT to GC transitions

Nonsysnonymous

I- > T

Calcr

6

3,650,125

A → G

AT to GC transitions

Essential splice site

C130060K24Rik

6

65,406,380

A → G

AT to GC transitions

Nonsysnonymous

K- > E

Wnk1

6

119,956,300

A → T

AT to TA transversions

Intronic

Vwf

6

125,576,322

G → A

GC to AT transitions

Nonsysnonymous

M- > I

Klrk1

6

129,566,794

G → A

GC to AT transitions

Intronic

Olfr1336

7

6,413,462

A → T

AT to TA transversions

Nonsysnonymous

T- > S

Nlrp9a

7

27,358,923

A → C

AT to CG transversions

Nonsysnonymous

E- > A

Arhgap33

7

31,315,480

C → T

GC to AT transitions

Synonymous

Gucy2d

7

105,600,256

A → T

AT to TA transversions

Exonic

7

146,105,909

T → C

AT to GC transitions

Intergenic

Rab11fip1

8

28,263,563

G → A

GC to AT transitions

Nonsysnonymous

P- > L

Nr3c2

8

79,741,251

T → C

AT to GC transitions

Intronic

Disc1

8

127,611,597

T → C

AT to GC transitions

Nonsysnonymous

L- > P

Prdm10

9

31,142,994

T → C

AT to GC transitions

Intronic

Olfr909

9

38,331,305

T → C

AT to GC transitions

Upstream

Olfr44

9

39,291,849

T → G

AT to CG transversions

3' UTR

Pou2f3

9

42,984,368

C → T

GC to AT transitions

Essential splice site

Dyx1c1

9

72,806,667

G → A

GC to AT transitions

5' UTR

Unc13c

9

73,582,186

T → C

AT to GC transitions

Intronic

Senp6

9

79,969,034

T → G

AT to CG transversions

Intronic

Cep63

9

102,521,076

T → C

AT to GC transitions

Intronic

Heca

10

17,635,364

T → C

AT to GC transitions

Nonsysnonymous

N- > S

Olig3

10

19,077,712

A → G

AT to GC transitions

3' UTR

Sobp

10

42,742,835

A → T

AT to TA transversions

Intronic

Serinc1

10

57,245,307

A → G

AT to GC transitions

Intronic

Sf3a2

10

80,263,982

A → G

AT to GC transitions

Nonsysnonymous

D- > G

Cyp27b1

10

126,485,434

T → C

AT to GC transitions

Nonsysnonymous

V- > A

Tns3

11

8,449,105

T → A

AT to TA transversions

5' UTR

Il5

11

53,537,612

C → T

GC to AT transitions

3' UTR

4930404A10Rik

11

54,185,249

T → A

AT to TA transversions

Nonsysnonymous

S- > R

Ulk2

11

61,615,130

A → T

AT to TA transversions

Intronic

Slc13a5

11

72,061,131

C → T

GC to AT transitions

Intronic

Ap2b1

11

83,183,124

G → A

GC to AT transitions

Intronic

Lrrc46

11

96,902,597

T → A

AT to TA transversions

5' UTR

Erbb2

11

98,297,347

T → C

AT to GC transitions

Synonymous

Krt40

11

99,401,666

A → G

AT to GC transitions

Intronic

Syngr2

11

117,674,256

T → A

AT to TA transversions

Intronic

Gm9229

12

18,193,251

C → A

GC to TA transversions

Genic

Mark3

12

112,885,660

T → C

AT to GC transitions

Intronic

Igh

12

115,853,922

T → A

AT to TA transversions

Genic

Tcrg-V4

13

19,282,580

A → C

AT to CG transversions

Genic

Aoah

13

21,003,081

A → T

AT to TA transversions

Intronic

Slc6a3

13

73,682,459

T → C

AT to GC transitions

Intronic

Gtf2h2

13

101,240,804

T → A

AT to TA transversions

Intronic

Ccdc125

13

101,449,272

A → G

AT to GC transitions

Nonsysnonymous

D- > G

3425401B19Rik

14

33,476,075

A → G

AT to GC transitions

Nonsysnonymous

I- > T

Mcpt1

14

56,637,381

G → T

GC to TA transversions

Intronic

Atp8a2

14

60,266,756

A → G

AT to GC transitions

Nonsysnonymous

Y- > H

Sorbs3

14

70,586,596

A → T

AT to TA transversions

Intronic

Epsti1

14

78,397,889

G → T

GC to TA transversions

Intronic

Diap3

14

87,384,824

G → T

GC to TA transversions

Intronic

Vps13b

15

35,570,473

A → G

AT to GC transitions

Intronic

Ubr5

15

37,898,017

A → G

AT to GC transitions

3' UTR

Micall1

15

78,960,399

G → A

GC to AT transitions

Intronic

Cyp2d12

15

82,387,610

A → T

AT to TA transversions

Intronic

Ttll1

15

83,320,020

G → A

GC to AT transitions

Stop gained

R- > X

Prkag1

15

98,643,692

A → G

AT to GC transitions

3' UTR

Gm7638

16

11,185,895

C → T

GC to AT transitions

Genic

Myh11

16

14,269,121

A → G

AT to GC transitions

Intronic

Gm6931

16

49,425,860

T → A

AT to TA transversions

Genic

16

80,727,008

A → C

AT to CG transversions

Intergenic

Olfr125

17

37,972,895

T → C

AT to GC transitions

Nonsysnonymous

I- > T

Enpp5

17

44,222,094

T → C

AT to GC transitions

Intronic

Gm7334

17

50,838,499

T → C

AT to GC transitions

Genic

Sult1c1

17

54,101,361

T → C

AT to GC transitions

3' UTR

2700099C18Rik

17

95,163,195

C → T

GC to AT transitions

Genic

Fhod3

18

25,248,741

A → G

AT to GC transitions

Nonsysnonymous

N- > S

Kdm3b

18

34,982,966

T → G

AT to CG transversions

Intronic

Pcdhb6

18

37,493,679

A → G

AT to GC transitions

Upstream

Pcdhga1

18

37,912,242

C → T

GC to AT transitions

Intronic

Spink10

18

62,820,759

G → T

GC to TA transversions

3' UTR

Cst6

19

5,344,061

A → T

AT to TA transversions

Intronic

Ganab

19

8,987,570

T → A

AT to TA transversions

Intronic

Cpsf7

19

10,607,448

G → T

GC to TA transversions

Intronic

Ms4a5

19

11,358,379

A → T

AT to TA transversions

Upstream

Ms4a14

19

11,382,160

A → T

AT to TA transversions

Genic

Tjp2

19

24,194,331

T → C

AT to GC transitions

Intronic

Cyp2c29

19

39,405,010

T → C

AT to GC transitions

3' UTR

Tll2

19

41,257,593

T → C

AT to GC transitions

Intronic

Sorcs3

19

48,768,473

A → C

AT to CG transversions

Nonsysnonymous

I- > L