Figure 4

Calbindin and parvalbumin cell densities and cell areas in the nucleus accumbens. Calbindin (CB) and parvalbumin (PV) cell densities and cell areas ± S.E.M. are presented for the nucleus accumbens (NAC). PV-positive cells and CB-positive cells are predominantly located in the shell and in the core of the NAC, respectively, where they were quantified. No statistically significant effect of a single adult methamphetamine challenge could be detected for either number (cell density) or cumulative size (cell area) of both PV and CB cells. Generally, the number of CB cells is considerably higher and their average size is doubled compared to PV cells.