From: Variation at APOE and STH loci and Alzheimer's disease
 | APOE genotypes | Exact P-values | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | ε 2/ε 3 | ε 2/ε 4 | ε 3/ε 3 | ε 3/ε 4 | ε 4/ε 4 | Total | ε 2/ε 3 | ε 2/ε 4 | ε 3/ε 3 | ε 3/ε 4 | ε 4/ε 4 | Total | |||||
 | f | N | f | N | f | N | f | N | f | N | N |  |  |  |  |  |  |
AD | 0.036 | 13 | 0.011 | 4 | 0.384 | 138 | 0.429 | 154 | 0.139 | 50 | 359 | 0.001 | 0.721 | 8.1*10-11 | 3.0*10-10 | 1.9*10-5 | 2.1*10-16 |
EOAD | 0.029 | 5 | 0.006 | 1 | 0.390 | 67 | 0.372 | 64 | 0.203 | 35 | 172 | 0.004 | 0.653 | 1.1*10-7 | 2.9*10-5 | 5.8*10-8 | 2.5*10-13 |
LOAD | 0.038 | 7 | 0.016 | 3 | 0.386 | 71 | 0.478 | 88 | 0.082 | 15 | 184 | 0.010 | 1.000 | 3.8*10-8 | 1.6*10-10 | 0.056 | 2.5*10-11 |
FH+ | 0.029 | 5 | 0.000 | 0 | 0.341 | 59 | 0.468 | 81 | 0.162 | 28 | 173 | 0.004 | 0.146 | 2.8*10-10 | 9.8*10-10 | 1.4*10-5 | 4.1*10-16 |
FH- | 0.039 | 7 | 0.022 | 4 | 0.425 | 77 | 0.392 | 71 | 0.122 | 22 | 181 | 0.010 | 0.727 | 3.3*10-6 | 3.5*10-6 | 0.001 | 6.1*10-9 |
Male | 0.043 | 6 | 0.021 | 3 | 0.390 | 55 | 0.447 | 63 | 0.099 | 14 | 141 | 0.053 | 1.000 | 1.8*10-5 | 1.8*10-6 | 0.099 | 6.3*10-7 |
Female | 0.032 | 7 | 0.005 | 1 | 0.381 | 83 | 0.417 | 91 | 0.165 | 36 | 218 | 0.015 | 0.559 | 1.7*10-6 | 6.4*10-5 | 8.7*10-5 | 8.9*10-10 |
EOAD vs. LOAD | 0.772 | 0.624 | 1.000 | 0.053 | 0.001 | 0.009 | |||||||||||
Controls | 0.106 | 26 | 0.016 | 4 | 0.654 | 161 | 0.187 | 46 | 0.037 | 9 | 246 | Â | Â | Â | Â | Â | Â |
Male | 0.113 | 13 | 0.017 | 2 | 0.661 | 76 | 0.165 | 19 | 0.043 | 5 | 115 | Â | Â | Â | Â | Â | Â |
Female | 0.099 | 13 | 0.015 | 2 | 0.649 | 85 | 0.206 | 27 | 0.031 | 4 | 131 | Â | Â | Â | Â | Â | Â |