From: Variation at APOE and STH loci and Alzheimer's disease
 | Number of ε 2 alleles | Chi-Square test for trend | Number of ε 3 alleles | Chi-Square test for trend | Number of ε 4 alleles | Chi-Square test for trend | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | 0 | 1 | 2 | χ 2 | P | 0 | 1 | 2 | χ 2 | P | 0 | 1 | 2 | χ 2 | P | |||||||||
 | f | N | f | N | f | N |  |  | f | N | f | N | f | N |  |  | f | N | f | N | f | N |  |  |
AD | 0.953 | 342 | 0.047 | 17 | 0 | 0 | 11.32 | 0.001 | 0.150 | 54 | 0.465 | 167 | 0.384 | 138 | 43.02 | < 0.0001 | 0.421 | 151 | 0.440 | 158 | 0.139 | 50 | Â | < 0.0001 |
EOAD | 0.965 | 166 | 0.035 | 6 | 0 | 0 | 9.73 | 0.002 | 0.209 | 36 | 0.401 | 69 | 0.390 | 67 | 37.41 | < 0.0001 | 0.419 | 72 | 0.378 | 65 | 0.203 | 35 | 56.72 | < 0.0001 |
LOAD | 0.946 | 174 | 0.054 | 10 | 0 | 0 | 5.69 | 0.017 | 0.098 | 18 | 0.516 | 95 | 0.386 | 71 | 26.27 | < 0.0001 | 0.424 | 78 | 0.494 | 91 | 0.082 | 15 | 42.63 | < 0.0001 |
FH+ | 0.971 | 168 | 0.029 | 5 | 0 | 0 | 11.46 | 0.001 | 0.162 | 28 | 0.497 | 86 | 0.341 | 59 | 41.06 | < 0.0001 | 0.370 | 64 | 0.468 | 81 | 0.162 | 28 | 61.13 | < 0.0001 |
FH- | 0.939 | 170 | 0.061 | 11 | 0 | 0 | 4.49 | 0.034 | 0.144 | 26 | 0.431 | 78 | 0.425 | 77 | 24.67 | < 0.0001 | 0.464 | 84 | 0.414 | 75 | 0.122 | 22 | 38.60 | < 0.0001 |
Male | 0.936 | 132 | 0.064 | 9 | 0 | 0 | 3.29 | 0.069 | 0.121 | 17 | 0.489 | 69 | 0.390 | 55 | 16.00 | < 0.0001 | 0.433 | 61 | 0.468 | 66 | 0.099 | 14 | 24.98 | < 0.0001 |
Female | 0.963 | 210 | 0.037 | 8 | 0 | 0 | 8.02 | 0.005 | 0.170 | 37 | 0.450 | 98 | 0.381 | 83 | 26.33 | < 0.0001 | 0.413 | 90 | 0.422 | 92 | 0.165 | 36 | 38.04 | < 0.0001 |
Controls | 0.878 | 216 | 0.122 | 30 | 0 | 0 | Â | Â | 0.053 | 13 | 0.293 | 72 | 0.654 | 161 | Â | Â | 0.760 | 187 | 0.203 | 50 | 0.037 | 9 | Â | Â |
Male | 0.870 | 100 | 0.130 | 15 | 0 | 0 | Â | Â | 0.061 | 7 | 0.278 | 32 | 0.661 | 76 | Â | Â | 0.774 | 89 | 0.183 | 21 | 0.043 | 5 | Â | Â |
Female | 0.885 | 116 | 0.115 | 15 | 0 | 0 | Â | Â | 0.046 | 6 | 0.305 | 40 | 0.649 | 85 | Â | Â | 0.748 | 98 | 0.221 | 29 | 0.031 | 4 | Â | Â |