Table 3 Performance on neuropsychological tests and correlationwith CTG repeat expansion*
From: Cognitive deficits and CTG repeat expansion size in classical myotonic dystrophy type 1 (DM1)
Test | DM1 (n = 47) | 1 SD < mean** | 2 SD < mean† | Spearman's Rho |
|---|---|---|---|---|
FAS | 35.0 (15.0) | 34.0 % | 2.1 % | -.02 |
RCFT (copy) | 31.0 (8.0) | 44.7 % | 36 % | -.34 † |
RCFT (delayed recall) | 16.5 (10.5) | 23.4 % | 21.3 % | -.09 |
Stroop CWT B (seconds) | 158.0 (54.0) | 57.5 % | 27.2 % | -.46† |
RAVLT (immediate recall) | 6.0 (9.0) | 34.0 % | 8.5 % | -.10 |
RAVLT (delayed recall) | 11.0 (4.0) | 10.6% | 0 % | .19 |
WCST (categories) | 3.0 (4.0) | 70.2 % | 17 % | -.38† |
TMT A (seconds) | 42.0 (20.0) | 61.7 % | 25.8 % | -.39† |
TMT B (seconds) | 101.0 (54.0) | 87.2 % | 63.8 % | -.30† |
WAIS-R: | ||||
Verbal subtests: | ||||
Information | 21.0 (8.0) | 6.4 % | 0 % | .08 |
Digit span | 12.0 (4.0) | 44.7 % | 8.5 % | -.03 |
Vocabulary | 45.0 (14.0) | 19.1 % | 0 % | -.34 † |
Arithmetic | 9.0 (4.0) | 40.5 % | 4.3 % | -.41 † |
Comprehension | 23.0 (6.0) | 8.5 % | 0 % | -.30 † |
Similarities | 19.0 (6.0) | 17 % | 0 % | -.09 |
Nonverbal subtests: | ||||
Picture completion | 16.0 (3.0) | 10.6 % | 0 % | -.08 |
Picture arrangement | 11.0 (7.0) | 25.5 % | 0 % | -.21 |
Block design | 20.0 (11.0) | 42.5 % | 2.1 % | -.09 |
Object assembly | 23.0 (15.0) | 53.2 % | 10.6 % | .04 |
Digit symbol | 40.0 (16.0) | 57.5 % | 4.3 % | -.23 |