Table 4 Genotype frequencies for polymorphisms in Table 3 for all phenotypic groups. Risk genotype indiciated by an *.
From: Number of risk genotypes is a risk factor for major depressive disorder: a case control study
rs6280 DRD3 | AA | AG | GG* |
|---|---|---|---|
controls | 46 (.55) | 34 (.41) | 3 (.04) |
depressed | 47 (.50) | 34 (.36) | 14 (.14) |
responder | 18 (.47) | 12 (.32) | 8 (.21) |
non-responder | 29 (.51) | 22 (.39) | 6 (.10) |
rs4680 COMT | AA | AG | GG* |
controls | 26 (.31) | 43 (.52) | 14 (.17) |
depressed | 30 (.32) | 34 (.36) | 30 (.32) |
responder | 12 (.32) | 13 (.35) | 12 (.32) |
non-responder | 18 (.31) | 21 (.37) | 18 (.31) |
rs165599 COMT | AA | AG | GG* |
controls | 46 (.56) | 30 (.37) | 6 (.07) |
depressed | 40 (.43) | 34 (.37) | 18 (.20) |
responder | 13 (.35) | 14 (.38) | 10 (.27) |
non-responder | 27 (.49) | 20 (.36) | 8 (.15) |
STin2 VNTR SLC6A4 | 10/10 | 10/12* | 12/12 |
controls | 15 (.18) | 25 (.31) | 42 (.51) |
depressed | 18 (.19) | 49 (.52) | 27 (.29) |
responder | 8 (.21) | 18 (.47) | 12 (.32) |
non-responder | 10 (.18) | 31 (.55) | 15 (.27) |
Exon 3 VNTR DRD4 | 0–7R* | 1–7R* | 2–7R |
controls | 56 (67) | 22 (.26) | 6 (.07) |
depressed | 55 (.57) | 36 (.38) | 5 (.05) |
responder | 15 (.38) | 21 (.54) | 3 (.08) |
non-responder | 40 (.70) | 15 (.26) | 2 (.04) |