Skip to main content

Table 3 Allelic association of D11S5028-V289I-D11S5027 and haplotype transmission test

From: Common variations in ALG9 are not associated with bipolar I disorder: a family-based study

Pedigree series

Haplotype

D11S5028 Allele (bp)

V289I Allele G TA>A TA

D11S5027 Allele (bp)

Expected haplotype frequency (no allelic association)

Observed haplotype frequency*

Haplotype transmission disequlibrium p-value

PITT

1.1.1

106

G

366

0.13

0.27

0.78

 

3.1.1

114

G

366

0.12

0.23

0.90

 

4.1.1

116

G

366

0.03

0.07

0.70

 

5.1.1

others

G

366

0.02

0.02

0.13

 

2.1.4

114

G

Others

0.01

0.02

0.81

 

2.2.2

110

A

372

0.02

0.22

0.82

 

2.2.3

110

A

375

0.05

0.05

0.55

NIMH

1.1

106

G

-

0.19

0.29

0.67

 

3.1

114

G

-

0.17

0.28

0.98

 

4.1

116

G

-

0.04

0.05

0.62

 

5.1

others

G

-

0.04

0.02

0.67

 

2.2

110

A

-

0.11

0.30

0.78

 

5.2

others

A

-

0.02

0.02

0.87

  1. *Only observed-haplotypes that have frequencies more than 2% are shown because the uncommon haplotypes, that have frequencies less than 2%, are not analyzed by TRANSMIT.