| NEO PI-R factors | STAI | |||||||
---|---|---|---|---|---|---|---|---|---|
Genotype | N (%) | Neuroticism | Extraversion | Openness | Agreeableness | Conscientiousness | N (%) | State Anxiety | Trait Anxiety |
DRD2 gene | |||||||||
   -241A/G polymorphism | |||||||||
   A/A | 197 (77.9) | 100.4 ± 20.7 | 97.3 ± 15.1 | 110.5 ± 14.3 | 112.9 ± 12.7 | 100.6 ± 16.6 | 184 (79.3) | 42.3 ± 9.7 | 44.6 ± 10.7 |
   A/G | 53 (20.9) | 94.6 ± 18.6 | 99.4 ± 12.3 | 108.7 ± 12.7 | 115.2 ± 14.3 | 102.6 ± 18.0 | 45 (19.4) | 38.8 ± 7.5 | 39.8 ± 8.9 |
   G/G | 3 (1.2) | 110.0 ± 17.1 | 98.0 ± 15.1 | 112.7 ± 17.7 | 120.3 ± 3.1 | 105.3 ± 12.7 | 3 (1.3) | 42.7 ± 7.5 | 45.3 ± 7.6 |
   -141C Ins/Del polymorphism | |||||||||
   Ins/Ins | 159 (62.6) | 98.0 ± 20.0 | 97.3 ± 14.2 | 109.3 ± 14.2 | 113.7 ± 12.4 | 102.0 ± 16.8 | 146 (62.7) | 42.7 ± 9.6* | 43.8 ± 10.5 |
   Ins/Del | 83 (32.7) | 101.4 ± 19.1 | 99.2 ± 15.0 | 111.5 ± 13.8 | 112.3 ± 14.5 | 99.4 ± 17.1 | 76 (32.6) | 39.8 ± 8.3 | 43.3 ± 10.3 |
   Del/Del | 12 (4.7) | 104.4 ± 25.1 | 92.7 ± 16.0 | 111.8 ± 10.5 | 119.9 ± 7.9 | 99.2 ± 15.7 | 11 (4.7) | 39.3 ± 11.8 | 45.7 ± 11.8 |
   Ser311Cys polymorphism | |||||||||
   Ser/Ser | 240 (94.5) | 99.6 ± 20.2 | 97.9 ± 14.6 | 110.5 ± 13.8 | 113.4 ± 13.1 | 100.7 ± 16.9 | 222 (94.9) | 41.8 ± 9.4 | 44.0 ± 10.5* |
   Ser/Cys | 14 (5.5) | 90.1 ± 11.8 | 96.3 ± 12.9 | 104.4 ± 14.7 | 117.7 ± 10.5 | 107.0 ± 9.9 | 12 (5.1) | 37.4 ± 7.9 | 37.1 ± 5.6 |
Ser9Gly polymorphism of the DRD3 gene | |||||||||
   Ser/Ser | 125 (52.5) | 99.8 ± 19.8 | 98.3 ± 15.3 | 110.4 ± 14.2 | 113.3 ± 13.3 | 101.5 ± 17.2 | 116 (53.2) | 41.3 ± 8.4 | 43.4 ± 9.4 |
   Ser/Gly | 92 (38.7) | 97.3 ± 19.8 | 97.7 ± 13.1 | 110.8 ± 13.8 | 114.1 ± 12.4 | 101.9 ± 17.1 | 82 (37.6) | 41.0 ± 10.1 | 42.6 ± 11.2 |
   Gly/Gly | 21 (8.8) | 103.3 ± 19.4 | 95.4 ± 15.4 | 106.9 ± 14.0 | 112.0 ± 15.0 | 93.5 ± 13.7 | 20 (9.2) | 44.7 ± 9.9 | 48.0 ± 12.5 |
TH gene | |||||||||
   Val81Met polymorphism | |||||||||
   Val/Val | 24 (12.4) | 96.5 ± 22.6 | 101.0 ± 17.0 | 108.2 ± 16.5 | 110.8 ± 8.8 | 98.7 ± 17.0 | 22 (12.4) | 42.0 ± 8.7 | 44.2 ± 10.4 |
   Val/Met | 80 (41.2) | 100.2 ± 17.5 | 96.1 ± 14.4 | 108.4 ± 15.2 | 115.2 ± 12.3 | 100.7 ± 16.7 | 74 (41.8) | 41.3 ± 7.5 | 45.1 ± 10.0 |
   Met/Met | 90 (46.4) | 100.1 ± 20.9 | 98.7 ± 13.6 | 111.0 ± 12.4 | 112.3 ± 12.8 | 98.7 ± 17.3 | 81 (45.8) | 40.8 ± 10.1 | 42.3 ± 10.5 |
   Pst I site polymorphism | |||||||||
   AA | 43 (18.4) | 96.2 ± 20.8 | 100.6 ± 14.4 | 112.5 ± 11.6 | 112.2 ± 12.1 | 99.9 ± 17.1 | 42 (19.0) | 40.6 ± 9.8 | 41.6 ± 11.1* |
   AB | 130 (55.5) | 100.8 ± 19.8 | 96.1 ± 14.5 | 109.3 ± 14.1 | 113.9 ± 14.0 | 100.6 ± 16.4 | 122 (55.2) | 41.8 ± 9.4 | 44.9 ± 10.3 |
   BB | 61 (26.1) | 96.9 ± 18.7 | 101.0 ± 14.2 | 109.6 ± 14.5 | 114.1 ± 9.8 | 101.4 ± 17.4 | 57 (25.8) | 41.3 ± 8.4 | 42.2 ± 10.0 |