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Table 1 Body weight and plasma concentrations of prolactin and haloperidol for control and haloperidol-treated rats

From: Haloperidol treatment induces tissue- and sex-specific changes in DNA methylation: a control study using rats

Sex Treatmenta Body weight (g) at Plasma concentrations of
   beginning end prolactin (ng/ml) haloperidol (ng/ml)
Male haloperidol 351.5 ± 6.9 476.0 ± 8.4 64.7 ± 43.7 4.3 ± 0.9b
  placebo 342.5 ± 6.3 473.0 ± 9.5 37.3 ± 10.0b 1.5, 2.0, <1.3c
Female haloperidol 211.0 ± 15.2 298.0 ± 16.9 441.1 ± 243.3 ND
  placebo 211.0 ± 12.9 300.0 ± 15.6 150.5 ± 112.7b ND
  1. aEach group consisted of 10 rats.
  2. bn = 5
  3. cHaloperidol was below the detection limit in three of the five rats examined.
  4. ND: not determined due to a high background activity of unknown origin.
  5. Plasma concentrations of prolactin and haloperidol were determined by the [125I]-labelled radioimmunoassay and colloidal gold immunoassay, respectively.