N | Genotype distribution (frequency) | Allele distribution (frequency) | HWE | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | CC | GC | GG | χ2 | P | C | G | χ2 | P | χ2 | P | |||||||
Patients | 352 | 11 | (0.03) | 130 | (0.37) | 211 | (0.60) | 9.09 | 0.011 | 152 | (0.22) | 552 | (0.78) | 7.00 | 0.008 | 2.90 | 0.089 | |
Controls | 362 | 28 | (0.08) | 144 | (0.40) | 190 | (0.52) | 200 | (0.28) | 524 | (0.72) | 0.01 | 0.921 | |||||
Male | ||||||||||||||||||
Patients | 211 | 9 | (0.04) | 79 | (0.37) | 123 | (0.58) | 2.27 | 0.322 | 97 | (0.23) | 325 | (0.77) | 0.20 | 0.655 | 0.70 | 0.404 | |
Controls | 112 | 9 | (0.08) | 37 | (0.33) | 66 | (0.59) | 55 | (0.25) | 169 | (0.75) | 1.31 | 0.252 | |||||
Female | ||||||||||||||||||
Patients | 141 | 2 | (0.01) | 51 | (0.36) | 88 | (0.62) | 10.12 | 0.006 | 55 | (0.20) | 227 | (0.80) | 8.54 | 0.003 | 3.26 | 0.071 | |
Controls | 250 | 19 | (0.08) | 107 | (0.43) | 124 | (0.50) | 145 | (0.29) | 355 | (0.71) | 0.39 | 0.534 |