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Table 2 Genotype and allele distributions of SNP2 (Thr98Ser) in patients with schizophrenia and controls for each sex

From: Association study of the vesicular monoamine transporter 1 (VMAT1) gene with schizophrenia in a Japanese population

   N Genotype distribution (frequency) Allele distribution (frequency) HWE
Total    CC GC GG χ2 P C G χ2 P χ2 P
  Patients 352 11 (0.03) 130 (0.37) 211 (0.60) 9.09 0.011 152 (0.22) 552 (0.78) 7.00 0.008 2.90 0.089
  Controls 362 28 (0.08) 144 (0.40) 190 (0.52)    200 (0.28) 524 (0.72)    0.01 0.921
Male                   
  Patients 211 9 (0.04) 79 (0.37) 123 (0.58) 2.27 0.322 97 (0.23) 325 (0.77) 0.20 0.655 0.70 0.404
  Controls 112 9 (0.08) 37 (0.33) 66 (0.59)    55 (0.25) 169 (0.75)    1.31 0.252
Female                   
  Patients 141 2 (0.01) 51 (0.36) 88 (0.62) 10.12 0.006 55 (0.20) 227 (0.80) 8.54 0.003 3.26 0.071
  Controls 250 19 (0.08) 107 (0.43) 124 (0.50)    145 (0.29) 355 (0.71)    0.39 0.534
  1. HWE: Hardy-Weinberg equilibrium
  2. Significant P values are underlined.