Figure 2

Females in proestrus are more sensitive to the PFC-impairing effects of stress than males or females in estrus. Animals were restrained for 0, 60 or 120 min prior to testing on the delayed alternation T-maze task. Results are represented as mean +/- SEM number correct. Mean scores after 0, 60 and 120 min restraint were 7.4 +/- .22, 7.6 +/- .3 and 5.7 +/- .51 for males; 7.1 +/- .18, 7.4 +/- .4 and 5.9 +/- .51 for females in estrus; and 6.9 +/- .2, 5 +/- .35 and 5.9 +/- .5 for females in proestrus. * = significantly different from self in control conditions, p < .05, ** = p < .005, *** = p < .0005, † = significantly different from self during estrus, p < .02.