Table 2 Polymorphism in genes in the families NRG and ErbB investigated in this study.
Gene | Chromosome | Size (kb) | No. of analysable SNPs | No. of SNPs with p < 0.101 | No. of SNPs with p < 0.051 |
|---|---|---|---|---|---|
NRG1 | 8 | 1120 | 94 | 22 (23%) | 11 (12%) |
NRG2 | 5 | 196 | 16 | 2 (13%) | 1 (6%) |
NRG3 | 10 | 1110 | 105 | 21 (20%) | 10 (10%) |
NRG4 | 15 | 70 | 9 | 0 | 0 |
EGFR | 7 | 188 | 22 | 7 (32%) | 6 (27%) |
ERBB2 | 17 | 29 | 4 | 1 (25%) | 0 |
ERBB3 | 12 | 23 | 6 | 0 | 0 |
ERBB4 | 2 | 1160 | 109 | 26 (24%) | 14 (13%) |