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Table 3 Percentages of pair-wise interactions that were significant (P < 0.05), classified by the gene(s) in which the interacting SNPs lie. Gene combinations in which there are substantially more significant interactions than the 5% expected by chance are indicated in bold. The counts that contribute to each percentage are also shown in parentheses as a fraction. The presence of "-" in the table indicates that no pairs of SNPs in this gene are 0.5 cM apart.

From: Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia

 

NRG1

NRG2

NRG3

EGFR

ERBB2

ERBB4

NRG1

5.8% (6/103)

13.6% (6/44)

11.7% (54/462)

4.5% (7/154)

0.0% (0/22)

7.9% (45/572)

NRG2

 

-

4.8% (2/42)

14.3% (2/14)

0.0% (0/2)

7.7% (4/52)

NRG3

  

5.7% (6/105)

2.0% (3/147)

0.0% (0/21)

8.4% (46/546)

EGFR

   

-

0.0% (0/7)

5.5% (10/182)

ERBB2

    

-

7.7% (2/26)

ERBB4

     

13.7% (19/139)