Kav | Frequency |
|---|
0.20 | 3/27 |
0.46 | 11/27 |
0.50 | 25/27 |
0.61 | 26/27 |
0.66 | 20/27 |
0.74 | 8/27 |
0.83 | 1/27 |
- The frequency of the low MW peak maxima typical for depressions analyzed by gel Filtration expressed as Kav values (A gel-filtration constant) is shown.
- Kav = Elution volume – Void volume/Total volume – Void volume. Depression shown here is of psychomotorically retarded psychotic depression. All were drug free and collected over 18 years.
- The great variation in peptide chain lengths with the same bio-activity from one patient to the next, makes it important to measure total hydrolysis releasable amino acids. This also increases the sensitivity of the assay because splitting peptide bonds increase the amino groups that can be coloured with ninhydrin [8].
