Towards a possible aetiology for depressions?

Table 3 Probable structure of some mass spectrometric peaks not shown in fig 5.

Kav of peak	Mass Found	Mass Expected	Structure	HPLC Co-chromatography with
0.61	579.6	579.6	Y-P-F-P-G-NH2	beta-casomorphineb 1–5 amide
0.66	522.3	522.3	Y-P-F-P	beta-casomorphineb 1–4
0.50	888.05	888.05	Y-P-F-P-G-P-I-P	beta-casomorphineb 1–8*
0.50	790.9	790.9	Y-P-F-P-G-P-I	beta-casomorphineb 1–7

b stands for bovine. * Imuno assay for casomorphine 1–8 with antibodies provided by Professor Dr Teschemacher, Giessen, Germany in 4 patients with this HPLC peak came to 120 fentomoles ± 30 (n = 4) while control values from the same peak area in 4 normal controls came to 15 ± 6 (n = 4).

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