Transgenic mice expressing constitutive active MAPKAPK5 display gender-dependent differences in exploration and activity

Table 3 Summary of the results.

Parameters	Female	Male	Effect on	Opposite
EPM
Head dips	6.86	-0.87	Female	Yes
% time open	8.65	-2.4	Female	Yes
% time closed	-8.11	3.23	Female	Yes
LD
Transitions	-1.48	2.92	Male	Yes
% time open	2.41	1.94	Female	No
% time closed	-2.41	-1.94	Female	No
Activity light	-13.6	46.97	Male	Yes

We compared TG mice to NTG mice per gender. A negative sign that indicates TG mice display a decreased response for a particular parameter compared to NTG mice. "Effect on" displays which gender is most affected, while "Opposite" indicates whether the behaviour of male mice is opposite to that observed in female mice.

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