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Figure 1 | Behavioral and Brain Functions

Figure 1

From: Increased sensitivity to cocaine-induced analgesia in Spontaneously Hypertensive Rats (SHR)

Figure 1

Cocaine-induced analgesia in Wistar and Spontaneously Hypertensive Rats in the hot-plate test. Male and female rats of Wistar (WIS) and Spontaneously Hypertensive Rats (SHR) strains were evaluated in the hot-plate test 15 min after i.p. injection of cocaine (20 mg/kg) (upper panel). SHR rats were habituated to the unheated hot-plate apparatus and 1 h after evaluated for CIA in the hot-plate test (lower panel). Data are presented as nociceptive latencies (s) or the percentage of maximum possible effects (%MPE). * p < 0.05 vs WIS rats of the corresponding gender (upper panel) or vs SHR naive rats (lower panel) (Newman-Keuls post hoc test).

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