Figure 9

PTPH1-KO hippocampus [76]. a: Hippocampus at 4×; b: CA1 area of hippocampus shows very intense LacZ staining in both oriens and radiatum layers and to a less extent in the pyramidal cell layer (20×; scale bar: 90 μm). c: CA2 area of hippocampus displays LacZ-positive staining in the pyramidal cell layer. d: CA3 area shows an intense beta-gal expression in the oriens and pyramidal cell layer, and in a less extent in the radiatum (20×). e: The dentate gyrus (DG) displays a strong LacZ staining in the molecular layer and not in the hilus (20×) (scale bar: 20 μm). pyr: pyramidal cell layer; oriens: oriens layer; rad: radiatum layer; mol: molecular layer: gr: granule cell layer; lac/mol: lacunosum-molecular layer.