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Table 1 Sample size for the unrelated sample and the related small nuclear families.

From: Recessive genetic mode of an ADH4 variant in substance dependence in African-Americans: A model of utility of the HWD test

     Sample sizes
   %Male Age (years) EA AA Hispanic Others
Sample 1 Healthy controls 39.9 28.2 ± 9.1 310 48   
  Cases 73.4 39.4 ± 9.2 391 158   
  AD 76.1 40.3 ± 9.2 326 101   
  DD 68.2 37.1 ± 8.1 204 145   
Sample 2 Healthy controls 28.0 33.5 ± 12.6   125   
  Cases 64.9 40.0 ± 9.3   271   
  AD 65.1 40.0 ± 9.3   269   
  DD 64.8 42.0 ± 8.3   71   
Sample 3 SNF size    92 12 6 2
  Parents 49.8 65.9 ± 8.6 183 24 11 3
  %Unaffected 45.5 66.8 ± 8.6 79.8 37.5 63.6 100.0
  Offspring 54.8 39.2 ± 11.1 96 13 5 1
  AD 58.9 37.3 ± 8.2 77 9 3 1
  DD 55.2 38.0 ± 7.3 77 13 5 1
  1. EA, European-American; AA, African-American; AD, alcohol dependence; DD, drug dependence; SNF, small nuclear families. Samples 1 and 2 are unrelated case-control samples; Sample 3 is related SNF sample.
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