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Table 1 Effect sizes (beta) per minor allele copy for RGS4 gene SNPs

From: Association of RGS4 variants with schizotypy and cognitive endophenotypes at the population level

  rs10917670
per A allele copy
rs951436
per G allele copy
rs2661319
per G allele copy
Response N beta Pall-load(P ANOVA ) N beta Pall-load(P ANOVA ) N beta Pall-load(P ANOVA )
IQ (RPM) 1470 -0.39 0.235 (0.349) 1595 0.17 0.603 (0.799) 1411 0.10 0.773 (0.715)
SPQ total score 1043 0.49 0.363 (0.607) 1134 -0.65 0.215 (0.455) 1004 -0.64 0.246 (0.502)
SPQ cognitive/perceptual factor 1041 0.00 0.553 (0.839) 1132 -0.00 0.807 (0.966) 1002 -0.00 0.514 (0.795)
SPQ negative factor 1041 0.01 0.184 (0.291) 1132 -0.01 0.009 (0.031) 1002 -0.01 0.039 (0.117)
SPQ disorganization factor 1041 0.01 0.256 (0.493) 1132 -0.01 0.266 (0.538) 1002 -0.01 0.262 (0.493)
SPQ paranoid factor 1041 0.00 0.980 (0.876) 1132 0.00 0.908 (0.881) 1002 0.00 0.896 (0.976)
d'-S2B (spatial working memory) 1434 -0.06 0.153 (0.352) 1558 -0.02 0.514 (0.650) 1384 -0.02 0.682 (0.900)
d'-V2B (verbal working memory) 1372 -0.05 0.124 (0.306) 1494 0.02 0.556 (0.285) 1324 0.01 0.755 (0.785)
Antisaccade error rate 1585 0.01 0.286 (0.565) 1731 -0.01 0.069 (0.173) 1532 -0.02 0.028 (0.089)
  1. SNP, single nucleotide polymorphism; ANOVA, analysis of variance; Pall-load, p value for the allele-load model; PANOVA, ANOVA p value. Strong linkage disequilibrium was observed between rs10917670 and rs951439 (r2 = 0.98). Results of rs951439 are not shown but are similar to rs 10917670.