Figure 1
From: Cross-fostering does not alter the neurochemistry or behavior of spontaneously hypertensive rats
Effect of cross-fostering on behavior in the open-field apparatus. *SHR pups (n = 12 – 14) travelled a greater distance (two-way ANOVA, significant effect of "pup strain", F(2,100) = 46, P < 0.0001, post-hoc Tukey's HSD test, P < 0.01), spent a longer period of time in the inner zone (two-way ANOVA, F(2,100) = 31, P < 0.0001, post-hoc Tukey's HSD test, P < 0.005) and entered the inner zone more frequently (two-way ANOVA, F(2,100) = 52, P < 0.0001, post-hoc Tukey's HSD test, P < 0.005) than WKY (n = 11 – 12) and SD (n = 10 – 15). SHR also entered the inner zone more rapidly than WKY (two-way ANOVA, F(2,100) = 30, P < 0.0001, post-hoc Tukey's HSD test, P < 0.0005). †SD pups travelled a greater distance (P < 0.0005), spent more time in the inner zone (P < 0.0005) and entered the inner zone more frequently (P < 0.0005) than WKY pups. SD entered the inner zone more rapidly than WKY (P < 0.0005). §Significantly different from SD reared by SHR or WKY (two-way ANOVA, significant interaction between "strain of dam" and "pup strain", F(4,100) > 2.8, P < 0.05, post-hoc Tukey's HSD test, P < 0.005). ‡Significantly less than SD reared by SHR, and SHR reared by WKY or SD (two-way ANOVA, significant dam*pup interaction, F(4,100) = 4.0, P < 0.005, post-hoc Tukey's HSD test, P < 0.005).