Impaired verbal memory in Parkinson disease: relationship to prefrontal dysfunction and somatosensory discrimination

Table 3 Group-differentiating principal component 7

PC	Core Anatomical Areas	Talairach Coordinates						PC Load	Group differences*	Functional Correlate
		R			L
		x	y	z	x	y	z
PC7	Dorsolateral prefrontal cortex	46	23	22				+	Norm-SSD vs. Patients-SSD (p < 0.02)	Working memory
	Mesial frontal cortex	1	45	23				+
	Middle temporal gyrus	50	-56	6				+
	Medio-dorsal Thalamus	2	-14	8				+
	Medial occipito-temporal gyrus				-5	-80	5	+
	Insular cortex	49	-9	12				+
	Superior occipital gyrus	18	-74	6				-

PC = Principal component. R = right, L = left hemisphere. PC load denotes positive (+) or negative (-) correlation of voxels at the given coordinates with the PC
*Norm-SSD: normal volunteers during somatosensory discrimination (SSD); Patients-SSD: patients during the same condition, unpaired t-test in PC expression coefficient.

ISSN: 1744-9081