|  |  | Emotional reactivity (ER) | Learning and memory (L&M) | Serotonergic (5-HT) measures | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
ER | 1) OF time in corners (mean 5 days) | r | 1.00 | -0.06 | -0.21 | -0.21 | -0.27 | 0.14 | 0.35 | -0.09 | -0.19 | 0.07 | -0.13 | 0.03 | 0.12 | 0.15 | 0.27 | 0.05 | -0.06 |
 |  | p |  | 0.73 | 0.24 | 0.24 | 0.13 | 0.44 | 0.05 | 0.61 | 0.29 | 0.70 | 0.47 | 0.89 | 0.51 | 0.42 | 0.13 | 0.80 | 0.76 |
 | 2) OF line crossings (mean 5 days) | r | -0.04 | 1.00 | 0.73 | -0.40 | -0.17 | 0.40 | 0.20 | 0.43 | 0.48 | -0.55 | 0.14 | 0.37 | 0.60 | -0.12 | 0.54 | 0.07 | 0.21 |
 |  | p | 0.82 |  | <0.01 | 0.02 | 0.36 | 0.02 | 0.28 | 0.01 | 0.01 | 0.00 | 0.45 | 0.04 | 0.00 | 0.52 | 0.00 | 0.70 | 0.24 |
 | 3) OF rearings & leanings (mean 5 days) | r | -0.17 | 0.82 | 1.00 | -0.49 | -0.18 | 0.66 | -0.12 | 0.39 | 0.72 | -0.69 | 0.20 | 0.46 | 0.55 | -0.48 | 0.43 | 0.24 | 0.44 |
 |  | p | 0.36 | <0.01 |  | 0.00 | 0.31 | <0.01 | 0.52 | 0.03 | <0.01 | <0.01 | 0.27 | 0.01 | 0.00 | 0.01 | 0.01 | 0.19 | 0.01 |
 | 4) EPM percent time in open arms (day 1) | r | -0.31 | -0.48 | -0.48 | 1.00 | 0.83 | -0.33 | 0.04 | -0.16 | -0.39 | 0.49 | -0.23 | -0.23 | -0.54 | 0.57 | -0.46 | -0.19 | -0.32 |
 |  | p | 0.08 | 0.01 | 0.01 |  | <0.01 | 0.07 | 0.84 | 0.38 | 0.03 | 0.00 | 0.20 | 0.21 | 0.00 | 0.00 | 0.01 | 0.30 | 0.08 |
 | 4) EPM percent entries open arms (day 1) | r | -0.30 | -0.24 | -0.25 | 0.86 | 1.00 | -0.20 | 0.02 | -0.21 | -0.16 | 0.32 | -0.24 | -0.03 | -0.44 | 0.41 | -0.38 | -0.25 | -0.30 |
 |  | p | 0.09 | 0.19 | 0.16 | <0.01 |  | 0.28 | 0.92 | 0.24 | 0.39 | 0.07 | 0.19 | 0.89 | 0.01 | 0.02 | 0.03 | 0.16 | 0.10 |
 | 6) EPM rearings & leanings (day 1) | r | 0.13 | 0.51 | 0.63 | -0.37 | -0.22 | 1.00 | 0.04 | 0.18 | 0.35 | -0.44 | 0.08 | 0.41 | 0.25 | -0.17 | 0.45 | 0.21 | 0.25 |
 |  | p | 0.47 | 0.00 | 0.00 | 0.04 | 0.24 |  | 0.81 | 0.32 | 0.05 | 0.01 | 0.65 | 0.02 | 0.17 | 0.37 | 0.01 | 0.25 | 0.17 |
 | 7) cLDB time in dark (mean 3 days) | r | 0.30 | 0.21 | -0.05 | 0.00 | 0.01 | 0.02 | 1.00 | -0.30 | -0.50 | 0.08 | -0.22 | 0.00 | 0.00 | 0.37 | 0.12 | -0.26 | -0.38 |
 |  | p | 0.09 | 0.24 | 0.80 | 0.98 | 0.95 | 0.90 |  | 0.10 | 0.00 | 0.65 | 0.22 | 0.99 | 0.98 | 0.04 | 0.50 | 0.15 | 0.03 |
 | 8) cLDB line crossings (mean 3 days) | r | -0.07 | 0.13 | 0.09 | -0.09 | -0.15 | 0.00 | -0.24 | 1.00 | 0.58 | -0.40 | 0.23 | 0.11 | 0.34 | -0.17 | 0.20 | 0.16 | 0.39 |
 |  | p | 0.70 | 0.49 | 0.61 | 0.62 | 0.40 | 1.00 | 0.20 |  | 0.00 | 0.02 | 0.21 | 0.55 | 0.05 | 0.36 | 0.26 | 0.38 | 0.03 |
 | 9) cLDB rearings & leanings (mean of 3 days) | r | -0.20 | 0.52 | 0.69 | -0.37 | -0.30 | 0.42 | -0.43 | 0.52 | 1.00 | -0.67 | 0.21 | 0.45 | 0.45 | -0.47 | 0.30 | 0.34 | 0.43 |
 |  | p | 0.27 | 0.00 | <0.01 | 0.04 | 0.10 | 0.02 | 0.01 | 0.00 |  | <0.01 | 0.25 | 0.01 | 0.01 | 0.01 | 0.10 | 0.06 | 0.01 |
L&M | 10) sMWM distance swum (mean 5 days) | r | 0.14 | -0.63 | -0.61 | 0.42 | 0.28 | -0.42 | 0.12 | -0.27 | -0.70 | 1.00 | -0.27 | -0.55 | -0.47 | 0.37 | -0.38 | -0.45 | -0.54 |
 |  | p | 0.46 | 0.00 | 0.00 | 0.02 | 0.12 | 0.02 | 0.50 | 0.14 | <0.01 |  | 0.13 | 0.00 | 0.01 | 0.04 | 0.03 | 0.01 | 0.00 |
 | 11) sMWM distance swum (lin. trend across 5 days) | r | 0.02 | 0.02 | 0.11 | -0.24 | -0.28 | 0.09 | -0.13 | 0.09 | 0.13 | -0.05 | 1.00 | -0.21 | 0.25 | -0.34 | 0.20 | 0.14 | 0.26 |
 |  | p | 0.93 | 0.91 | 0.54 | 0.19 | 0.12 | 0.61 | 0.49 | 0.63 | 0.47 | 0.80 |  | 0.24 | 0.17 | 0.06 | 0.26 | 0.43 | 0.16 |
 | 12) sMWM probe trial time in training annulus | r | 0.10 | 0.24 | 0.28 | -0.24 | -0.11 | 0.28 | -0.25 | -0.02 | 0.39 | -0.39 | -0.33 | 1.00 | 0.05 | 0.02 | 0.19 | 0.23 | 0.14 |
 |  | p | 0.60 | 0.19 | 0.12 | 0.20 | 0.55 | 0.12 | 0.16 | 0.91 | 0.03 | 0.03 | 0.06 |  | 0.80 | 0.92 | 0.31 | 0.21 | 0.44 |
 | 13) raMWM delta (odd-even trials) (mean 5 days) | r | 0.13 | 0.56 | 0.52 | -0.51 | -0.37 | 0.21 | -0.11 | 0.14 | 0.42 | -0.37 | 0.20 | -0.06 | 1.00 | -0.38 | 0.42 | 0.23 | 0.42 |
 |  | p | 0.48 | 0.00 | 0.00 | 0.00 | 0.04 | 0.24 | 0.54 | 0.45 | 0.02 | 0.04 | 0.27 | 0.74 |  | 0.03 | 0.02 | 0.20 | 0.02 |
 | 14) PA log latency entry dark, retention | r | 0.13 | -0.15 | -0.43 | 0.41 | 0.36 | -0.13 | 0.31 | -0.12 | -0.40 | 0.24 | -0.35 | 0.13 | -0.30 | 1.00 | -0.36 | -0.07 | -0.37 |
 |  | p | 0.50 | 0.42 | 0.01 | 0.02 | 0.04 | 0.49 | 0.09 | 0.53 | 0.03 | 0.19 | 0.06 | 0.50 | 0.10 |  | 0.05 | 0.70 | 0.04 |
5-HT | 15) 5-HT turnover (5-HIAA.5-HT-1) in hipp. | r | 0.18 | 0.46 | 0.38 | -0.33 | -0.17 | 0.36 | 0.01 | 0.01 | 0.22 | -0.35 | 0.23 | 0.16 | 0.12 | -0.30 | 1.00 | 0.33 | 0.30 |
 |  | p | 0.31 | 0.01 | 0.03 | 0.06 | 0.35 | 0.05 | 0.95 | 0.96 | 0.23 | 0.05 | 0.21 | 0.39 | 0.52 | 0.10 |  | 0.07 | 0.10 |
 | 16) 5-HT in cortex | r | 0.07 | 0.14 | 0.25 | -0.16 | -0.17 | 0.25 | -0.29 | 0.14 | 0.32 | -0.42 | 0.06 | 0.28 | 0.26 | 0.06 | 0.27 | 1.00 | 0.76 |
 |  | p | 0.70 | 0.46 | 0.17 | 0.39 | 0.34 | 0.18 | 0.10 | 0.44 | 0.07 | 0.02 | 0.73 | 0.12 | 0.16 | 0.74 | 0.14 |  | <0.01 |
 | 17) 5-HIAA in cortex | r | -0.04 | 0.31 | 0.42 | -0.26 | -0.26 | 0.26 | -0.43 | 0.22 | 0.42 | -0.52 | 0.16 | 0.15 | 0.51 | -0.20 | 0.22 | 0.78 | 1.00 |
 |  | p | 0.82 | 0.08 | 0.02 | 0.15 | 0.16 | 0.16 | 0.02 | 0.22 | 0.02 | 0.00 | 0.38 | 0.40 | 0.00 | 0.28 | 0.23 | <0.01 |  |