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Table 3 ADHD and externalizing symptoms: main effect tests of high, intermediate and low activity 5HTTLPR genotypes.

From: Gene × environment interactions for ADHD: synergistic effect of 5HTTLPR genotype and youth appraisals of inter-parental conflict

  High Intermediate Low p pe peas
N 78 137 89    
KSAD Diagnostics
Inattentive Symptoms 5.5 (3.5) 6.0 (3.2) 5.5 (3.7) .49 .51 .22
Hyperactive Symptoms 3.7 (3.3) 3.8 (3.3) 4.2 (3.3) .60 .47 .52
ODD Symptoms 1.7 (2.3) 1.6 (2.2) 1.8 (2.4) .81 .80 .83
CD Symptoms .33 (.65) .57 (1.3) .30 (.87) .10 .09 .09
Conners' Teacher Report
Cognitive Problems 3.0 (3.5) 3.4 (4.0) 3.8 (4.7) .47 .45 .44
Hyperactivity 4.3 (4.8) 3.6 (3.8) 3.1 (3.8) .20 .24 .13
ADHD Rating Scale Teacher Report
Inattention 4.6 (6.7) 4.3 (6.1) 4.9 (6.5) .95 .96 .93
Hyperactivity 3.1 (5.9) 2.4 (4.5) 2.3 (4.6) .49 .65 .46
  1. Note. High activity genotypes (La/La); Intermediate activity genotypes (La/Lg, La/short); Low activity genotypes (Lg/Lg, Lg/short, short/short.) pe = ethnicity corrected p value, peas = ethnicity age, and sex corrected p value. Inattentive, Hyperactive, ODD, and CD symptoms are parent report on the KSADS-E. Conners' Scores and ADHD Rating Scale scores are raw total scores on each measure (higher scores signify symptoms/problems).