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Table 1 Demographic and clinical description of subjects

From: Depression in Myotonic Dystrophy type 1: clinical and neuronal correlates

 

DM1 (n = 31)

Contrast group (n = 47)

Age

41.8 (9.5, 23-58)

43.5 (15.0, 18-64)

Sex

14 M, 17 F

15 M, 32 F

Education (years)

10.9 (2.2, 8-18)

10.4 (1.8, 9-15)

Age at onset

26.2 (8.7, 15-50)

17 (14.5, 0-60)

Disease duration (years)

16.8 (10.7, 3-38)

27 (16, 5-60)

CTG-repeats

578 (401, 100-2000)

-

Fatigue*

25 (81%)

-

MIRS**

3.6 (0.8, 1-5)

-

Grip force (Newton)

104 (48, 20-144)

-

Brooke-rating††

0.5 (1.1)

5.9 (13.9)

  1. * Patients scoring the presence of abnormal fatigue in a self-rating procedure described in Winblad et al, 2005 [9].
  2. ** Muscular Impairment Rating Scale [17]. This score ranges from 1 (no muscular impairment) to 5 (severe proximal weakness).
  3. Scores on a handgrip force measurement using the Grippit instrument. Mean (SD) for healthy controls = 331 (77) Newton [16].
  4. †† Brookes functional test and grading system, zero implies normal function and higher values indicates increasing levels of immobility [18].
  5. Data in Table 1 is presented as mean, standard deviation and range.