Figure 2

Location of the four SNPs analyzed in and around the HERG1 gene on 7q36.1 region. a: The 100 kb genomic region (shown as horizontal gray line) including the HERG1 gene (shown as gray rectangle) on 7q36.1. b: The organization of exons (shown as gray boxes) and introns (shown as horizontal gray lines) of the HERG1 gene. The four SNPs analyzed span ~76 kb on genomic DNA in chr7:150225599-150302147 bp position. Two SNPs (rs885684 and rs956642) are located at the 3'-downstream intergenic region of HERG1, and the other two SNPs (rs1805123 and rs3800779) are located respectively in exon 11 and intron 2 of the gene. Black circles (●) represent the SNP locations, and the rs numbers of SNPs are shown along the relevant arrows. SNP, single nucleotide polymorphism.