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Table 1 Genotype and allele frequencies and results of the association analysis between patients and controls.

From: Two four-marker haplotypes on 7q36.1 region indicate that the potassium channel gene HERG1 (KCNH2, Kv11.1) is related to schizophrenia: a case control study

SNP

Genotype frequencies, n (%)

χ2

P-value

Allele frequencies

χ2

P-value

 

Genotype

SCH (n = 84)

CTR (n = 74)

  

Allele

SCH (n = 84)

CTR (n = 74)

  

rs885684

AA

37 (44.0)

34 (45.9)

1.06

0.302

A/C

0.696/0.304

0.642/0.358

1.06

0.303

 

AC

43 (51.2)

27 (36.5)

       
 

CC

4 (4.8)

13 (17.6)

       

rs956642

AA

37 (44.0)

28 (37.8)

2.38

0.123

A/G

0.679/0.321

0.595/0.405

2.41

0.120

 

AG

40 (47.6)

32 (43.2)

       
 

GG

7 (8.3)

14 (19.0)

       

rs1805123

AA

51 (60.7)

39 (52.7)

2.12

0.145

A/C

0.792/0.208

0.723/0.277

2.03

0.153

 

AC

31 (36.9)

29 (39.2)

       
 

CC

2 (2.4)

6 (8.1)

       

rs3800779

GG

37 (44.1)

49 (66.2)

5.15

0.023

G/T

0.673/0.327

0.791/0.209

5.52

0.018

 

GT

39 (46.4)

19 (25.7)

       
 

TT

8 (9.5)

6 (8.1)

       
  1. SNP, single nucleotide polymorphism; SCH, patients with schizophrenia; CTR, control subjects.
  2. Alleles shown are major/minor.
  3. The P-values given are corrected by means of Bonferroni correction.
  4. Association reaching nominal significance (P < 0.05) is shown in bold.