Table 1 Demographic and baseline characteristics (safety population) by last dose in the dose-optimization phase
Characteristic, mean (SD) | LDX 30 mg/d (n = 28) | LDX 50 mg/d (n = 70) | LDX 70 mg/d (n = 44) | LDX All Doses (N = 142) |
|---|---|---|---|---|
Age (years) | 30.5 (9.54) | 29.7 (10.71) | 31.8 (11.46) | 30.5 (10.70) |
Weight (lb) | 174.7 (43.64) | 176.7 (35.22) | 182.4 (36.17) | 178.1 (37.14) |
Height (in) | 65.8 (4.30) | 68.3 (3.73) | 68.3 (3.77) | 67.8 (3.97) |
Body mass index (lb/in2) | 28.2 (5.45) | 26.6 (4.79) | 27.4 (5.10) | 27.2 (5.02) |
Gender, n(%) | Â | Â | Â | Â |
   Male/female | 16 (57.1)/12 (42.9) | 45 (64.3)/25 (35.7) | 27 (61.4)/17 (38.6) | 88 (62.0)/54 (38.0) |
Race, n (%) | ||||
   White | 21 (75.0) | 65 (92.9) | 41 (93.2) | 127 (89.4) |
   Black/African American | 4 (14.3) | 2 (2.9) | 0 | 6 (4.2) |
   Native Hawaiian/Pacific Islander | 2 (7.1) | 0 | 0 | 2 (1.4) |
   Asian | 1 (3.6) | 2 (2.9) | 2 (4.5) | 5 (3.5) |
   American Indian/Alaskan Native | 0 | 0 | 1 (2.3) | 1 (0.7) |
   Other | 0 | 1 (1.4) | 0 | 1 (0.7) |
Ethnicity, n (%) | ||||
Hispanic or Latino/ Not Hispanic or Latino | 2 (7.1)/26 (92.9) | 7 (10.0)/63 (90.0) | 4 (9.1)/40 (90.9) | 13 (9.2)/129 (90.8) |
ADHD subtype, n (%) | ||||
   Inattentive | 8 (28.6) | 20 (28.6) | 11 (25.0) | 39 (27.5) |
   Hyperactive/impulsive | 1 (3.6) | 3 (4.3) | 1 (2.3) | 5 (3.5) |
   Combined | 19 (67.9) | 47 (67.1) | 32 (72.7) | 98 (69.0) |
ADHD-RS-IV with adult prompts: scores at baseline, mean (SD) | Â | Â | Â | Â |
   Total | 37.8 (6.06) | 35.8 (4.85) | 38.4 (6.12) | 37.0 (5.61) |
   Inattentive | 20.9 (3.15) | 19.7 (3.45) | 20.8 (3.66) | 20.3 (3.49) |
   Hyperactivity/impulsivity | 16.9 (5.52) | 16.1 (4.35) | 17.6 (4.86) | 16.7 (4.77) |