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Table 3 Predose and average postdose PERMP scores: PERMP total, PERMP-A, and PERMP-C (n = 104)

From: Randomized, double-blind, placebo-controlled, crossover study of the efficacy and safety of lisdexamfetamine dimesylate in adults with attention-deficit/hyperactivity disorder: novel findings using a simulated adult workplace environment design

 

Predose PERMP Mean

(SD)

Average Postdose PERMP Mean

(SD)

Difference in Postdose LS Mean

(95% CI)

(LDX/Placebo)

P Value

PERMP total

   While receiving LDX

260.1 (86.23)

312.7 (94.42)

23.4 (15.6, 31.2)

< .0001

   While receiving placebo

261.4 (74.96)

287.6 (81.45)

  

PERMP-A

   While receiving LDX

132.2 (43.28)

158.4 (47.53)

12.0 (8.1, 15.8)

< .0001

   While receiving placebo

132.6 (37.62)

145.7 (41.06)

  

PERMP-C

   While receiving LDX

127.9 (43.02)

154.3 (46.96)

11.5 (7.6, 15.4)

< .0001

   While receiving placebo

128.8 (37.39)

141.9 (40.44)

  
  1. CI = confidence interval; LDX = lisdexamfetamine dimesylate; LS = least squares; PERMP = Permanent Product Measure of Performance; PERMP-A = PERMP-Attempted; PERMP-C = PERMP-Correct.