Table 2 SPM analyses performed in the subgroup of 23 women. k is the cluster size expressed in voxels.
From: 5-HT1A gene promoter polymorphism and [18F]MPPF binding potential in healthy subjects: a PET study
| Â | 23 women | ||
|---|---|---|---|
contrast | anatomic brain regions covered | MNI coordinates (x, y, z (mm)) | Z score, k, p |
GG-CC | left anterior superior and middle frontal gyri (F1 and F2) | -16; 16; 52 | Z = 4.48, k = 239, p = 0.042* |
| Â | right and left orbitofrontal cortex | 22; 58; -12 | Z = 4.31, k = 550, p = 0.001* |
GG-CG | right and left mesial frontal pole | 4; 62; 8 | Z = 5.04, k = 1884, p < 0.001* |
| Â | right anterior second and third temporal cortex (T2, T3) | 60; -22; -18 | Z = 4.61, k = 416, p = 0.004* |
| Â | right orbitofrontal cortex | 28; 40; -18 | Z = 4.48, k = 313, p = 0.014* |
| Â | right dorsolateral frontal cortex | 44; 38; 26 | Z = 3.94, k = 365, p = 0.007* |
CC-GG | NS | ||
CC-CG | NS | ||
CG-CC | NS | ||
CG-GG | NS | ||
GG-(CG+CC) | right and left mesial frontal pole | 4; 62; 8 | Z = 4.79, k = 1407, p < 0.001* |
| Â | right anterior second and third temporal cortex (T2, T3) | 60; -22; -18 | Z = 4.52, k = 283, p = 0.022* |
| Â | left anterior superior and middle frontal gyri (F1 and F2) | -16; 16; 52 | Z = 4.35, k = 253, p = 0.034* |
| Â | right orbitofrontal cortex | 28; 40; -18 | Z = 4.29, k = 298, p = 0.018* |
| Â | right dorsolateral frontal cortex | 44; 38; 26 | Z = 3.92, k = 324, p = 0.012* |
| Â | left anterior inferior frontal gyrus (F3) | -46; 40; 4 | Z = 3.74, k = 312, p = 0.015* |
(CG+CC)-GG | NS | ||