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Table 3 Dopaminergic polymorphisms and borderline personality symptoms in the Hungarian patient sample

From: Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients

 

Genotype

N

BPD score ± STD

F

df

p

η2

power

COMT

Met/Met

34

4.79 ± 2.54

0.367

2,131

0.694

0.006

0.108

 

Met/Val

70

4.71 ± 2.29

     
 

Val/Val

32

5.16 ± 2.57

     

DAT1

9/9

11

4.64 ± 2.87

0.120

2,131

0.887

0.002

0.068

40 bp

9/10

48

4.75 ± 2.74

0.082

1,132

0.775

0.001

0.059

VNTR

10/10*

77

4.92 ± 2.13

     

DRD2

B1/B1

3

3.33 ± 3.22

1.712

2,131

0.184

0.025

0.355

TaqIB

B1/B2

37

5.38 ± 2.31

1.518

1,132

0.220

0.011

0.231

 

B2/B2

96

4.68 ± 2.40

     

TaqID

C/C

27

4.30 ± 2.54

1.490

2,131

0.229

0.022

0.313

 

C/T

59

5.31 ± 2.28

     
 

T/T

50

4.58 ± 2.43

     

TaqIA

A1/A1

4

3.75 ± 2.75

0.460

2,131

0.632

0.007

0.124

 

A1/A2

41

4.90 ± 2.56

0.001

1,132

0.970

0

0.050

 

A2/A2

91

4.86 ± 2.34

     

DRD4

1/1

4

3.25 ± 2.06

1.611

2,131

0.204

0.024

0.336

120 bp

1/2

40

5.18 ± 2.18

1.604

1,132

0.208

0.012

0.242

dup

2/2

92

4.76 ± 2.50

     

-616

C/C

44

5.48 ± 2.45

5.146

2,131

0.007

0.073

0.818

 

C/G

56

4.80 ± 2.36

8.152

1,132

0.005

0.058

0.809

 

G/G

36

4.11 ± 2.27

     

-521

C/C

34

5.00 ± 2.54

0.463

2,131

0.630

0.007

0.124

 

C/T

65

4.62 ± 2.38

0.354

1,132

0.553

0.003

0.091

 

T/T

37

5.08 ± 2.37

     

48 bp

7/7

3

5.67 ± 1.53

0.282

2,131

0.754

0.004

0.094

VNTR

one 7

35

4.77 ± 2.38

0.134

1,132

0.715

0.001

0.065

 

no 7

98

4.84 ± 2.45

     

Haplotype

0

68

4.40 ± 2.34

3.602

2,131

0.030

0.052

0.658

-616 C ~

1

50

5.14 ± 2.46

6.969

1,132

0.009

0.050

0.746

-521 T

2

18

5.67 ± 2.30

     
  1. The mean ± SD of the sum of borderline symptoms (BPD score) from the self-report SCID-II Screen questionnaire are presented for the different genotype groups. Where it is indicated, in the second set of univariate ANOVAs rare homozygote genotypes (n < 5) or literature-based genotypes were grouped together with the heterozygotes for the fixed factor; sex and age were used as covariates.
  2. * At the DAT1 VNTR one 10/11 and one 10/12 sample were grouped together with the 10/10 (9-allele absent) genotype group.