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Table 2 Genotype association of DTNBP1 SNP rs9370822

From: A polymorphism in the dysbindin gene (DTNBP1) associated with multiple psychiatric disorders including schizophrenia

Sample Set

Genotype counts

p-value*

 

AA (%)

AC (%)

CC (%)

 

control

113 (47.9)

101 (42.8)

22 (9.3)

 

Schizophrenia ‡

58 (37.2)

66 (42.3)

32 (20.5)

0.004

0.002†

Odds ratio

1.00

1.27

2.83

 

p-value

 

0.57

0.002

 

PTSD

36 (30)

62 (51.7)

22 (18.3)

0.002

0.0004†

Odds ratio

1.00

1.93

3.14

 

p-value

 

0.02

0.00

 

Nicotine dependence

46 (33.8)

70 (51.5)

20 (14.7)

0.022

0.007†

Odds ratio

1.00

1.70

2.23

 

p-value

 

0.04

0.05

 

Opiate dependence

45 (39.8)

47 (41.6)

21 (18.6)

0.04

0.027†

Odds ratio

1.00

1.17

2.40

 

p-value

 

1.00

0.03

 

Alcohol dependence

92 (41.63)

103 (46.6)

26 (11.76)

0.36

0.16†

Odds ratio

1.00

1.25

1.45

 

p-value

 

0.51

0.49

 
  1. * p-value determined by Pearson's χ2 test
  2. † p-value determined using the extended Mantel-Haenszel test for trend
  3. ‡ previously published data [24]
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Behavioral and Brain Functions

ISSN: 1744-9081

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