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Table 1 Genotype distribution of SNPs of the ALOX12 gene among schizophrenia patients in a Korean population.

From: Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population

SNP Amino acid Genotype Control
N = 306
Schizophrenia
N = 289
Model OR 95% CI p
    Freq. % Freq. %    LCL UCL  
rs1126667 R261Q G/G 96 31.4 77 26.6 Codominant 1.09 0.75 1.59 0.048
(Exon 6)   A/G 151 49.4 132 45.7 Dominant 1.26 0.88 1.80 0.200
   A/A 59 19.3 80 27.7 Recessive 1.60 1.09 2.35 0.015*
rs434473 S322N A/A 96 31.4 78 27.0 Codominant 1.09 0.74 1.58 0.073
(Exon 8)   A/G 153 50.0 135 46.7 Dominant 1.24 0.87 1.76 0.240
   G/G 57 18.6 76 26.3 Recessive 1.56 1.06 2.30 0.025*
rs1042357 T364T C/C 95 31.1 77 26.6 Codominant 1.07 0.73 1.57 0.050*
(Exon 8) A/C 152 49.7   132 45.7 Dominant 1.24 0.87 1.77 0.240
   A/A 59 19.3 80 27.7 Recessive 1.60 1.09 2.35 0.015*
  1. ALOX12, arachidonate 12-lipoxygenase; R, arginine; Q, glutamine; S, serine; N, asparagine; T, threonine; Freq, frequency; OR, odds ratio; CI, confidence interval; LCL, lower confidence limit; UCL, upper confidence limit; p, probability value.
  2. *These values are not significant after the Bonferroni correction (number of tests = 18).