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Table 2 Genotype distribution of ALOX12 gene SNPs among schizophrenia patients in a Korean population.

From: Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population

SNP Amino acid Genotype Negative(+)
N = 168
Negative(-)
N = 121
χ2 df P
    Freq. % Freq. %    
rs1126667 R261Q G/G 41 24.4 36 29.8    
(Exon 6)   A/G 86 51.2 46 38.0 4.984 2 0.083
   A/A 41 24.4 39 32.2    
rs434473 S322N A/A 41 24.4 37 30.6    
(Exon 8)   A/G 89 53.0 46 38.0 6.428 2 0.040*
   G/G 38 22.6 38 31.4    
rs1042357 T364T C/C 41 24.4 36 29.8    
(Exon 8)   A/C 86 51.2 46 38.0 4.984 2 0.083
   A/A 41 24.4 39 32.2    
  1. ALOX12, arachidonate 12-lipoxygenase; R, arginine; Q, glutamine; S, serine; N, asparagine; T, threonine; Freq, frequency; df, degree of freedom; p, probability value.
  2. *The value is not significant after the Bonferroni correction (number of test = 18).
  3. Negative symptom subgroup identified by factor analysis of OPCRIT data.