Skip to main content

Table 2 Genotype distribution of ALOX12 gene SNPs among schizophrenia patients in a Korean population.

From: Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population

SNP

Amino acid

Genotype

Negative†(+)

N = 168

Negative†(-)

N = 121

χ2

df

P

   

Freq.

%

Freq.

%

   

rs1126667

R261Q

G/G

41

24.4

36

29.8

   

(Exon 6)

 

A/G

86

51.2

46

38.0

4.984

2

0.083

  

A/A

41

24.4

39

32.2

   

rs434473

S322N

A/A

41

24.4

37

30.6

   

(Exon 8)

 

A/G

89

53.0

46

38.0

6.428

2

0.040*

  

G/G

38

22.6

38

31.4

   

rs1042357

T364T

C/C

41

24.4

36

29.8

   

(Exon 8)

 

A/C

86

51.2

46

38.0

4.984

2

0.083

  

A/A

41

24.4

39

32.2

   
  1. ALOX12, arachidonate 12-lipoxygenase; R, arginine; Q, glutamine; S, serine; N, asparagine; T, threonine; Freq, frequency; df, degree of freedom; p, probability value.
  2. *The value is not significant after the Bonferroni correction (number of test = 18).
  3. †Negative symptom subgroup identified by factor analysis of OPCRIT data.