Table 3 Genotypes of TPH2 rs7305115 polymorphism and HDRS scores in MDD+suicide group (scores, mean ± SD)
From: Effect of Tryptophan Hydroxylase-2 rs7305115 SNP on suicide attempts risk in major depression
| Â | Genotype | P value | ||
|---|---|---|---|---|
| Â | AA | AG | GG | Â |
Anxiety/Somatization | l2.83 ± 4.03 | l2.11 ± 3.72 | l2.01 ± 3.83 | 0.113 |
Loss of weight | 1.81 ± 0.54 | 1.78 ± 0.54 | 1.55 ± 0.48 | 0.832 |
Cognitive impairment | 7.90 ± 3.97 | 10.05 ± 4.23 | 10.93 ± 3.82 | 0.035 |
Diurnal change | 1.76 ± 1.27 | 1.67 ± 1.26 | 1.45 ± 0.97 | 0.223 |
Slow movement | 10.23 ± 2.41 | 9.15 ± 2.33 | 9.38 ± 2.75 | 0.468 |
Sleep disorders | 5.61 ± 0.66 | 5.24 ± 0.71 | 5.60 ± 0.85 | 0.176 |
Hopelessness | 9.60 ± 2.12 | 11.57 ± 1.80 | 11.29 ± 2.10 | 0.032 |
HDRS scores in sum | 49.80 ± l0.57 | 51.49 ± l0.71 | 52.28 ± l0.83 | 0.092 |