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Table 3 Genotype and allele frequencies of the ADORA2A gene SNPs in patients and controls.

From: The adenosine A2A receptor is associated with methamphetamine dependence/psychosis in the Japanese population

SNP Group N Genotype (%)    P Allele (%)   P
Exon1+179 (rs13306114) C/C C/C C/T   T/T C T
  Control 229 229 (100.0%) 0 (0.0%) 0 (0.0%)   458 (100.0%) 0 (0.0%)  
  METH 171 168 (98.2%) 3 (1.8%) 0 (0.0%) 0.132 339 (99.1%) 3 (0.9%) 0.154
Exon1+219 C/C C/T T/T   C T  
  Control 229 228 (99.6%) 1 (0.4%) 0 (0.0%)   457 (99.8%) 1 (0.2%)  
  METH 171 169 (98.8%) 2 (1.2%) 0 (0.0%) 0.701 340 (99.4%) 2 (0.6%) 0.807
IVS1+64 (rs13306116) G/G G/A A/A   G A  
  Control 229 219 (95.6%) 10 (4.4%) 0 (0.0%)   448 (97.8%) 10 (2.2%)  
  METH*1 171 162 (94.7%) 8 (4.7%) 1 (0.6%) 0.504 332 (97.1%) 10 (2.9%) 0.663
Exon2+751 (rs5751876) T/T T/C C/C   T C  
  Control 229 70 (30.6%) 114 (49.8%) 45 (19.7%)   254 (55.5%) 204 (44.5%)  
  METH 171 35 (20.5%) 85 (49.7%) 51 (29.8%) 0.018 155 (45.3%) 187 (54.7%) 0.0057
IVS2+28 (rs34923252) T/T T/A A/A   T A  
  Control 229 181 (79.0%) 43 (18.8%) 5 (2.2%)   405 (88.4%) 53 (11.6%)  
  METH 171 144 (84.2%) 26 (15.2%) 1 (0.6%) 0.258 314 (91.8%) 28 (8.2%) 0.146
  1. *1: METH sample: Hardy-Weinberg Equilibrium p = 0.0214
  2. N: Number of samples
  3. P: Significance values between METH samples and controls.