Table 3 Genotype and allele frequencies of the ADORA2A gene SNPs in patients and controls.

Exon1+179 (rs13306114)

C/C

C/C

C/T

C

T

Control

229

229 (100.0%)

0 (0.0%)

0 (0.0%)

458 (100.0%)

0 (0.0%)

METH

171

168 (98.2%)

3 (1.8%)

0 (0.0%)

0.132

339 (99.1%)

3 (0.9%)

0.154

Exon1+219

C/C

C/T

T/T

C

T

Control

229

228 (99.6%)

1 (0.4%)

0 (0.0%)

457 (99.8%)

1 (0.2%)

METH

171

169 (98.8%)

2 (1.2%)

0 (0.0%)

0.701

340 (99.4%)

2 (0.6%)

0.807

IVS1+64 (rs13306116)

G/G

G/A

A/A

G

A

Control

229

219 (95.6%)

10 (4.4%)

0 (0.0%)

448 (97.8%)

10 (2.2%)

METH*¹

171

162 (94.7%)

8 (4.7%)

1 (0.6%)

0.504

332 (97.1%)

10 (2.9%)

0.663

Exon2+751 (rs5751876)

T/T

T/C

C/C

T

C

Control

229

70 (30.6%)

114 (49.8%)

45 (19.7%)

254 (55.5%)

204 (44.5%)

METH

171

35 (20.5%)

85 (49.7%)

51 (29.8%)

0.018

155 (45.3%)

187 (54.7%)

0.0057

IVS2+28 (rs34923252)

T/T

T/A

A/A

T

A

Control

229

181 (79.0%)

43 (18.8%)

5 (2.2%)

405 (88.4%)

53 (11.6%)

METH

171

144 (84.2%)

26 (15.2%)

1 (0.6%)

0.258

314 (91.8%)

28 (8.2%)

0.146