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Table 5 Association analyses between the Exon2+751 (rs5751876) SNP and clinically subcategorized METH subjects

From: The adenosine A2A receptor is associated with methamphetamine dependence/psychosis in the Japanese population

Samples

Subgroups

N

Genotype (%)

P1

P2

   

T

T/C

C

  

Control

 

229

70 (31%)

114 (50%)

45 (20%)

  

METH

Latency of Psychosis

      
 

   < 3 years

64

15 (23%)

32 (50%)

17 (27%)

0.366

 
 

   ≥ 3 years

70

17 (24%)

30 (43%)

23 (33%)

0.068

0.663

 

Prognosis of Psychosis

      
 

   Transient (< 1 month)

91

21 (23%)

40 (44%)

30 (33%)

0.036

 
 

   Prolonged (≥ 1 month)

56

11 (20%)

34 (61%)

11 (20%)

0.231

0.115

 

Spontaneous Relapse

      
 

   Not present

104

22 (21%)

50 (48%)

32 (31%)

0.046

 
 

   Present

60

12 (20%)

31 (52%)

17 (28%)

0.167

0.905

 

Multiple Drug Usage

      
 

   None (METH use only)

52

6 (12%)

29 (56%)

17 (33%)

0.0099

 
 

   Poly-drugs

112

26 (23%)

54 (48%)

32 (29%)

0.127

0.214

  1. N: Number of samples
  2. P1: Significance values between METH samples and controls.
  3. P2: Significance values between the subgroups in each clinical category