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Table 5 Association analyses between the Exon2+751 (rs5751876) SNP and clinically subcategorized METH subjects

From: The adenosine A2A receptor is associated with methamphetamine dependence/psychosis in the Japanese population

Samples Subgroups N Genotype (%) P1 P2
    T T/C C   
Control   229 70 (31%) 114 (50%) 45 (20%)   
METH Latency of Psychosis       
     < 3 years 64 15 (23%) 32 (50%) 17 (27%) 0.366  
     ≥ 3 years 70 17 (24%) 30 (43%) 23 (33%) 0.068 0.663
  Prognosis of Psychosis       
     Transient (< 1 month) 91 21 (23%) 40 (44%) 30 (33%) 0.036  
     Prolonged (≥ 1 month) 56 11 (20%) 34 (61%) 11 (20%) 0.231 0.115
  Spontaneous Relapse       
     Not present 104 22 (21%) 50 (48%) 32 (31%) 0.046  
     Present 60 12 (20%) 31 (52%) 17 (28%) 0.167 0.905
  Multiple Drug Usage       
     None (METH use only) 52 6 (12%) 29 (56%) 17 (33%) 0.0099  
     Poly-drugs 112 26 (23%) 54 (48%) 32 (29%) 0.127 0.214
  1. N: Number of samples
  2. P1: Significance values between METH samples and controls.
  3. P2: Significance values between the subgroups in each clinical category