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Table 1 Demographic and clinical characteristics of subjects with ADHD

From: Possible association of norepinephrine transporter -3081(A/T) polymorphism with methylphenidate response in attention deficit hyperactivity disorder

 

ADHD

(n = 112)

Responders

(n = 62)

Non-responders

(n = 50)

p-value

Age in yr, mean (SD)

9.1 (2.1)

9.1 (2.0)

9.0 (2.2)

0.79

Sex (M/F)

92/20

54/8

38/12

0.13

IQ, mean (SD)

107.4 (13.7)

107.8 (13.2)

106.9 (14.4)

0.73

ADHD subtypes

   

0.30

   Combined

61.6%

58.1%

66.0%

 

   Inattentive

25.9%

25.8%

26.0%

 

   Hyperactive-impulsive

5.4%

4.8%

6.0%

 

   NOS

7.1%

11.3%

2.0%

 

Comorbidity

    

   Oppositional defiant disorder

13.4%

8.0%

20.0%

0.07

   Anxiety disorder

10.7%

9.7%

12.0%

0.69

   Enuresis

4.5%

6.5%

2.0%

0.26

ARS baseline scores, mean (SD)

    

   Total

26.9 (10.3)

25.9 (11.1)

28.3 (8.8)

0.23

   Inattentive

15.1 (5.8)

14.2 (5.9)

16.3 (5.6)

0.07

   Hyperactivity/impulsivity

11.8 (6.0)

11.6 (6.3)

12.0 (5.7)

0.75

Dosage of MPH (mg/day), mean (SD)

    

   Baseline dose

19.9 (8.3)

18.6 (6.2)

21.5 (10.1)

0.08

   Final 2 weeks dose

29.2 (11.6)

28.2 (10.9)

30.4 (12.4)

0.32

  1. ADHD, Attention-Deficit/Hyperactivity Disorder; NOS, Not Otherwise Specified; ARS, ADHD Rating Scale; MPH, Methylphenidate