Effects of pretreatments with isotonic saline (0.9% NaCl), L-NAME (40 μg) or L-ARGININE (20 μg) in rats submitted to central injection of ANG-II (26 ng) or isotonic saline on mean arterial pressure (MAP). Eight to ten animals were used in each group. Differences among groups were determined by Two-Way ANOVA followed by the Newman-Keuls post test. Data are reported as means ± SEM. *P < 0.05 compared to the control group (Saline + Saline). *P < 0.05 compared to the control group (Saline+Saline). #P < 0.05 compared to the Saline+L-NAME group. +P < 0.05 compared to the Saline+ANG-II group.