Effects of AAH inhibition or over-expression on cell type specific gene expression. P2 Long Evans rat pups were administered intracerebroventricular injections of (A-E) siAAH or siScr, or (F-J) recombinant plasmid pAAH or pGFP cDNA. Cerebellar tissue harvested from P21 rats was used to measure mRNA levels of (A, F) Hu, (B, G) tau, (C, H) GFAP, and (D, I) MAG-1, and (E, J) 18S rRNA by qRT-PCR. The graphs in Panels A-D and F-I depict calculated mRNA/18S ratios, and those in Panels E and J represent the mean ng rRNA input into the reactions. Panels display box plots with means and minimum-maximum whiskers. Inter-group statistical comparisons were made using Student T-tests. Significant P-values are indicated within the panels.