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Table 2 Involved activation areas of Mean Component Images 1 and 2 with a cluster size >20 voxels.

From: Neural networks engaged in tactile object manipulation: patterns of expression among healthy individuals

Functional Region Anatomical Region x y z Cluster Size Max. Load Conjunction Images
Mean Component Image 1        conMCI 1 conMCI 1S
MI, SI and premotor c., L Pre-and postcentral g. -40 -20 58 1545 +0.0109 ++ ++
Paralimbic ACC, R/L Medial superior frontal g. 0 3 42 61 +0.0061 ++ -
SI, R Postcentral g. 61 -21 14 22 +0.0060 ++ -
Cerebellum, R Anterior cerebellum (Lobule VI) 20 -57 -14 25 +0.0060 ++ -
Temporal pole, R Superior temporal g. 55 13 -9 78 +0.0069 + -
Inferior parietal c., R Inferior parietal lobule 50 -60 44 426 -0.0051 + +
   Superior parietal c., R Superior parietal lobule 38 -59 56   -0.0034 + -
Superior parietal c., L Superior parietal lobule -40 -58 53 194 -0.0039 + -
   Inferior parietal c., L Inferior parietal lobule -50 -58 42   -0.0038 + -
   Temporal-parieto-occipital c. Superior temporal g. -51 -59 29   -0.0036 + -
Medial prefrontal c., R Medial superior frontal g. 10 36 52 93 -0.0041 + +
Medial prefrontal c., L Medial superior frontal g. -4 60 28 82 -0.0040 + +
Precuneus, R/L Precuneus 0 -54 38 763 -0.0050 + +
   Posterior cingulate c., R, L Posterior cingulate g. 0 -53 23   -0.0042 + -
Cerebellum, L Cerebellum posterior lobe (Lobule VIIa, Crus I) -40 -81 -25 23 -0.0037 + -
Dorso-lateral prefrontal c., R Middle frontal g. 46 21 39 68 -0.0037 + +
Dorso-lateral prefrontal c., L Middle frontal g. -40 31 37 29 -0.0036 + -
        Additional Areas
SII, R Postcentral g. -60 18 16    + -
SII, L Postcentral g. 60 20 19    + -
SMA, R Medial superior frontal g. 5 4 42    + -
CMA, L Middle cingulate g. 0 10 35    + -
Mean Component Image 2        conMCI 2 conMCI 2S
MI, SI, L Pre- and postcentral g. -42 -17 56 95 +0.0072 ++ ++
Cuneus, R, L Cuneus 0 -94 14 69 +0.0098 ++ -
Precuneus, R, L Precuneus 0 -51 58 229 +0.0080 ++ ++
Lingual g., L Lingual g. -14 -94 -9 253 +0.0076 + -
Thalamus, R/L Midline thalamic nuclei 0 -21 8 607 +0.0132 ++ +
Pontine reticular formation, R Rostral pons (dorsal/medial) 14 -34 -18 56 +0.0076 - -
Parabrachial nuclei, R/L Rostral pons (dorsal/lateral) 0 -40 -22 89 +0.0095 ++ -
Cerebellum, R Cerebellum posterior lobe (Lobule VIIa, Crus I) 42 -80 -16 255 +0.0096 ++ -
MI, R Precentral g. 61 -8 26 87 -0.0044 + -
Cuneus, R Cuneus 16 -84 34 196 -0.0043 + +
MI, L Precentral g. -59 -4 28 51 -0.0039 + -
Cuneus, L Cuneus -12 -68 29 840 -0.0051 + -
   Lingual g., L Lingual g. 16 -54 1   -0.0049 + +
Lingual g., R Lingual g. 26 -66 -3 408 -0.0048 + +
   Parahippocampal g., R Parahippocampal g. 22 -54 -1   -0.0044 + +
Ventral premotor c., L Inferior frontal g. -48 16 18 56 -0.0041 + -
        Additional Areas
Superior parietal c., L Superior parietal lobule -36 -42 63    + -
Inferior parietal c., L Inferior parietal lobule -50 -40 54    + -
CMA, L Middle cingulate c. -2 7 32    + -
  1. Functional regions are ordered according to following criteria: (1) positive loads; (2) negative loads; (3a) central -anterio-posterior cortices, i.e. primary sensorimotor areas first, followed by areas of the frontal lobes, the parietal lobes, (3b) subcortical structures and (3c) cerebellum. Indented areas belong to the preceding cluster. Coordinates (x,y,z) are given in Talairach space. The two rightmost columns represent the presence of a given brain area in the conjunction images (see Fig. 5); where '++' = 100% overlap, '+' = 50% overlap, '-' = no overlap. MCI: mean component image; conMCI: conjunction of PCS that constitute a mean component image; conMCIS: conjunction of PCs that correlate significantly with a given MCI, but were not included in its computation (see Methods for details). 'Additional Areas' lists areas present in the conjunctions, but not the MCI. pACC: paralimbic anterior cingulate cortex; CMA: cingulate motor area; MI: primary motor cortex; SI: primary somatosensory cortex; SII: secondary somatosensory cortex; SMA; supplementary motor area c.: cortex; g.: gyrus; R: right; L: left. (...) according to Schmahmann's nomenclature of the cerebellum [60]